Nat Cell Biol · 2018

Recognition of RNA N<sup>6</sup>-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

Huang H, Weng H, Sun W, Qin X, Shi H, Wu H, Zhao BS, Mesquita A, Liu C, Yuan CL, Hu YC, Hüttelmaier S, Skibbe JR, Su R, Deng X, Dong L, Sun M, Li C, Nachtergaele S, Wang Y, Hu C, Ferchen K, Greis KD, Jiang X, Wei M, Qu L, Guan JL, He C, Yang J, Chen J.

Show affiliations
  • Huang H — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Weng H — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Sun W — Key Laboratory of Gene Engineering of the Ministry of Education, Sun Yat-sen University, Guangzhou, China.
  • Qin X — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Shi H — Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
  • Wu H — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Zhao BS — Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
  • Mesquita A — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Liu C — Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
  • Yuan CL — Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Hu YC — Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Hüttelmaier S — Institute of Molecular Medicine, Department of Molecular Cell Biology, Martin Luther University, Halle, Germany.
  • Skibbe JR — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Su R — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Deng X — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Dong L — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Sun M — Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Li C — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Nachtergaele S — Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
  • Wang Y — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Hu C — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Ferchen K — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Greis KD — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Jiang X — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Wei M — Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.
  • Qu L — Key Laboratory of Gene Engineering of the Ministry of Education, Sun Yat-sen University, Guangzhou, China.
  • Guan JL — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • He C — Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.
  • Yang J — Key Laboratory of Gene Engineering of the Ministry of Education, Sun Yat-sen University, Guangzhou, China. yangjh7@mail.sysu.edu.cn.
  • Chen J — Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA. jianchen@coh.org.
18 read8 want to readRigor 2.5Novelty 2.8Impact 3.7Reprod. 2.8

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Tariq Silva

Rigor 1/5Novelty 5/5Impact 3/5Reprod. 2/5

Great figures and clear story.

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Eva Silva

Rigor 5/5Novelty 1/5Impact 3/5Reprod. 2/5

Nice but incremental.

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Ken Park

Rigor 1/5Novelty 1/5Impact 1/5Reprod. 4/5

Important contribution to the field.

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Ravi Smith

Rigor 1/5Novelty 3/5Impact 3/5Reprod. 3/5

Important contribution to the field.