Science · 2018

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

Gootenberg JS, Abudayyeh OO, Kellner MJ, Joung J, Collins JJ, Zhang F.

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  • Gootenberg JSBroad Institute of the Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA 02142, USA.
  • Abudayyeh OOBroad Institute of the Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA 02142, USA.
  • Kellner MJBroad Institute of the Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA 02142, USA.
  • Joung JBroad Institute of the Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA 02142, USA.
  • Collins JJBroad Institute of the Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA 02142, USA.
  • Zhang FBroad Institute of the Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA 02142, USA. zhang@broadinstitute.org.
62 read12 want to readRigor 3.1Novelty 3.1Impact 2.8Reprod. 2.9

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0

Yuki Khan

Rigor 3/5Novelty 2/5Impact 3/5Reprod. 1/5

Important contribution to the field.

0

Pablo Patel

Rigor 1/5Novelty 4/5Impact 2/5Reprod. 2/5

Nice but incremental.

0

Sam Brown

Rigor 3/5Novelty 5/5Impact 5/5Reprod. 1/5

Solid methods, convincing results.

0

Hugo Nguyen

Rigor 4/5Novelty 5/5Impact 3/5Reprod. 5/5

Interesting idea, small sample.

0

Lena Kim

Rigor 1/5Novelty 3/5Impact 2/5Reprod. 3/5

Interesting idea, small sample.

0

Noor Wang

Rigor 5/5Novelty 4/5Impact 2/5Reprod. 3/5

Solid methods, convincing results.

0

Ines Wang

Rigor 5/5Novelty 1/5Impact 4/5Reprod. 2/5

Important contribution to the field.

0

Hugo Wang

Rigor 3/5Novelty 5/5Impact 1/5Reprod. 3/5

Nice but incremental.

0

Pablo Sato

Rigor 3/5Novelty 2/5Impact 4/5Reprod. 5/5

Replication is unclear to me.

0

Tariq Brown

Rigor 5/5Novelty 2/5Impact 2/5Reprod. 5/5

Replication is unclear to me.

0

Noor Cohen

Rigor 5/5Novelty 2/5Impact 4/5Reprod. 2/5

Replication is unclear to me.

0

Noor Rossi

Rigor 1/5Novelty 3/5Impact 1/5Reprod. 2/5

Solid methods, convincing results.

0

Tariq Kim

Rigor 1/5Novelty 4/5Impact 2/5Reprod. 4/5

Replication is unclear to me.

0

Hugo Mueller

Rigor 5/5Novelty 5/5Impact 4/5Reprod. 4/5

Solid methods, convincing results.