Nature · 2017

RNA targeting with CRISPR-Cas13

Abudayyeh OO, Gootenberg JS, Essletzbichler P, Han S, Joung J, Belanto JJ, Verdine V, Cox DBT, Kellner MJ, Regev A, Lander ES, Voytas DF, Ting AY, Zhang F.

Show affiliations
  • Abudayyeh OOBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Gootenberg JSBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Essletzbichler PBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Han SDepartments of Genetics, Biology, and Chemistry, Stanford University, Stanford, California 94305, USA.
  • Joung JBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Belanto JJDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA.
  • Verdine VBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Cox DBTBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Kellner MJBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Regev ABroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Lander ESBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Voytas DFDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA.
  • Ting AYDepartments of Genetics, Biology, and Chemistry, Stanford University, Stanford, California 94305, USA.
  • Zhang FBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
5 read1 want to readRigor 2.4Novelty 3.0Impact 3.6Reprod. 2.8

Most-cited papers citing this

  • BMC Med · 2025 · cited by 12
  • Cell · 2025 · cited by 6
  • Genes (Basel) · 2025 · cited by 5
  • J Am Chem Soc · 2025 · cited by 5
  • Front Neurol · 2025 · cited by 3

Log in to like, log, and share thoughts on this paper.

Discussion

Share your thoughts above to start a thread. Constructive feedback only — reply to and like others’ posts.

0

Mei Brown

Rigor 1/5Novelty 3/5Impact 5/5Reprod. 5/5

Solid methods, convincing results.