Nature · 2016

The antibody aducanumab reduces Aβ plaques in Alzheimer's disease

Sevigny J, Chiao P, Bussière T, Weinreb PH, Williams L, Maier M, Dunstan R, Salloway S, Chen T, Ling Y, O'Gorman J, Qian F, Arastu M, Li M, Chollate S, Brennan MS, Quintero-Monzon O, Scannevin RH, Arnold HM, Engber T, Rhodes K, Ferrero J, Hang Y, Mikulskis A, Grimm J, Hock C, Nitsch RM, Sandrock A.

Show affiliations
  • Sevigny JBiogen, Cambridge, Massachusetts 02142, USA.
  • Chiao PBiogen, Cambridge, Massachusetts 02142, USA.
  • Bussière TBiogen, Cambridge, Massachusetts 02142, USA.
  • Weinreb PHBiogen, Cambridge, Massachusetts 02142, USA.
  • Williams LBiogen, Cambridge, Massachusetts 02142, USA.
  • Maier MNeurimmune, Schlieren-Zurich 8952, Switzerland.
  • Dunstan RBiogen, Cambridge, Massachusetts 02142, USA.
  • Salloway SButler Hospital, Providence, Rhode Island 02906, USA.
  • Chen TBiogen, Cambridge, Massachusetts 02142, USA.
  • Ling YBiogen, Cambridge, Massachusetts 02142, USA.
  • O'Gorman JBiogen, Cambridge, Massachusetts 02142, USA.
  • Qian FBiogen, Cambridge, Massachusetts 02142, USA.
  • Arastu MBiogen, Cambridge, Massachusetts 02142, USA.
  • Li MBiogen, Cambridge, Massachusetts 02142, USA.
  • Chollate SBiogen, Cambridge, Massachusetts 02142, USA.
  • Brennan MSBiogen, Cambridge, Massachusetts 02142, USA.
  • Quintero-Monzon OBiogen, Cambridge, Massachusetts 02142, USA.
  • Scannevin RHBiogen, Cambridge, Massachusetts 02142, USA.
  • Arnold HMBiogen, Cambridge, Massachusetts 02142, USA.
  • Engber TBiogen, Cambridge, Massachusetts 02142, USA.
  • Rhodes KBiogen, Cambridge, Massachusetts 02142, USA.
  • Ferrero JBiogen, Cambridge, Massachusetts 02142, USA.
  • Hang YBiogen, Cambridge, Massachusetts 02142, USA.
  • Mikulskis ABiogen, Cambridge, Massachusetts 02142, USA.
  • Grimm JNeurimmune, Schlieren-Zurich 8952, Switzerland.
  • Hock CNeurimmune, Schlieren-Zurich 8952, Switzerland.
  • Nitsch RMNeurimmune, Schlieren-Zurich 8952, Switzerland.
  • Sandrock ABiogen, Cambridge, Massachusetts 02142, USA.
51 read8 want to readRigor 3.0Novelty 3.1Impact 3.1Reprod. 2.8

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Discussion

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0

Jonas Silva

Rigor 5/5Novelty 3/5Impact 5/5Reprod. 4/5

Replication is unclear to me.

0

Lena Silva

Rigor 4/5Novelty 4/5Impact 5/5Reprod. 3/5

Important contribution to the field.

0

Maya Kim

Rigor 3/5Novelty 4/5Impact 3/5Reprod. 1/5

Interesting idea, small sample.

0

Mei Kim

Rigor 3/5Novelty 3/5Impact 5/5Reprod. 4/5

Important contribution to the field.

0

Hugo Kim

Rigor 1/5Novelty 5/5Impact 2/5Reprod. 1/5

Important contribution to the field.

0

Sara Kim

Rigor 1/5Novelty 5/5Impact 5/5Reprod. 5/5

Great figures and clear story.

0

Pablo Garcia

Rigor 2/5Novelty 5/5Impact 2/5Reprod. 3/5

Great figures and clear story.

0

Sam Patel

Rigor 1/5Novelty 2/5Impact 5/5Reprod. 4/5

Important contribution to the field.

0

Hugo Lee

Rigor 5/5Novelty 1/5Impact 1/5Reprod. 5/5

Replication is unclear to me.

0

Alex Nguyen

Rigor 3/5Novelty 5/5Impact 1/5Reprod. 1/5

Nice but incremental.

0

Lena Nguyen

Rigor 5/5Novelty 4/5Impact 5/5Reprod. 1/5

Replication is unclear to me.

0

Tom Cohen

Rigor 4/5Novelty 2/5Impact 1/5Reprod. 1/5

Interesting idea, small sample.

0

Jonas Cohen

Rigor 4/5Novelty 4/5Impact 3/5Reprod. 4/5

Replication is unclear to me.

0

Noor Rossi

Rigor 2/5Novelty 3/5Impact 3/5Reprod. 3/5

Nice but incremental.

0

Noor Kim

Rigor 2/5Novelty 1/5Impact 3/5Reprod. 5/5

Solid methods, convincing results.

0

Ines Wang

Rigor 4/5Novelty 3/5Impact 3/5Reprod. 1/5

Interesting idea, small sample.