Nat Nanotechnol · 2020

Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing

Cheng Q, Wei T, Farbiak L, Johnson LT, Dilliard SA, Siegwart DJ.

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  • Cheng QDepartment of Biochemistry, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Wei TDepartment of Biochemistry, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Farbiak LDepartment of Biochemistry, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Johnson LTDepartment of Biochemistry, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Dilliard SADepartment of Biochemistry, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Siegwart DJDepartment of Biochemistry, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX, USA. Daniel.Siegwart@UTSouthwestern.edu.
35 read5 want to readRigor 2.7Novelty 2.9Impact 2.9Reprod. 2.9

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0

Jonas Nguyen

Rigor 4/5Novelty 3/5Impact 2/5Reprod. 2/5

Solid methods, convincing results.

0

Ines Rossi

Rigor 5/5Novelty 5/5Impact 2/5Reprod. 4/5

Nice but incremental.

0

Alex Kim

Rigor 1/5Novelty 2/5Impact 1/5Reprod. 5/5

Interesting idea, small sample.

0

Omar Patel

Rigor 2/5Novelty 4/5Impact 4/5Reprod. 2/5

Interesting idea, small sample.

0

Yuki Kim

Rigor 3/5Novelty 1/5Impact 1/5Reprod. 3/5

Great figures and clear story.

0

Tom Smith

Rigor 2/5Novelty 4/5Impact 2/5Reprod. 1/5

Replication is unclear to me.

0

Noor Mueller

Rigor 3/5Novelty 2/5Impact 2/5Reprod. 1/5

Important contribution to the field.

0

Noor Kim

Rigor 2/5Novelty 2/5Impact 4/5Reprod. 1/5

Replication is unclear to me.