Nat Genet · 2017

Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells

Meyers RM, Bryan JG, McFarland JM, Weir BA, Sizemore AE, Xu H, Dharia NV, Montgomery PG, Cowley GS, Pantel S, Goodale A, Lee Y, Ali LD, Jiang G, Lubonja R, Harrington WF, Strickland M, Wu T, Hawes DC, Zhivich VA, Wyatt MR, Kalani Z, Chang JJ, Okamoto M, Stegmaier K, Golub TR, Boehm JS, Vazquez F, Root DE, Hahn WC, Tsherniak A.

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Meyers RM — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Bryan JG — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
McFarland JM — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Weir BA — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Sizemore AE — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Xu H — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Dharia NV — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Montgomery PG — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Cowley GS — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Pantel S — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Goodale A — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Lee Y — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Ali LD — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Jiang G — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Lubonja R — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Harrington WF — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Strickland M — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Wu T — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Hawes DC — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Zhivich VA — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Wyatt MR — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Kalani Z — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Chang JJ — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Okamoto M — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Stegmaier K — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Golub TR — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Boehm JS — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Vazquez F — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Root DE — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Hahn WC — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Tsherniak A — Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.