Nat Biotechnol · 2015
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
Tsai SQ, Zheng Z, Nguyen NT, Liebers M, Topkar VV, Thapar V, Wyvekens N, Khayter C, Iafrate AJ, Le LP, Aryee MJ, Joung JK.
Show affiliations
- Tsai SQ — Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA USA.
- Zheng Z — Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA USA.
- Nguyen NT — Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA USA.
- Liebers M — Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA USA.
- Topkar VV — Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA USA.
- Thapar V — Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA USA.
- Wyvekens N — Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA USA.
- Khayter C — Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA USA.
- Iafrate AJ — Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA USA.
- Le LP — Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA USA.
- Aryee MJ — Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA USA.
- Joung JK — Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA USA.
78 read8 want to readRigor 2.8Novelty 2.8Impact 3.1Reprod. 2.7
Most-cited papers citing this
- Cardiovasc Res · 2025 · cited by 7
- Front Neurol · 2025 · cited by 3
- Nat Rev Genet · 2026 · cited by 3
- Cancer Cell · 2025 · cited by 3
- Nat Biomed Eng · 2026 · cited by 3
Log in to like, log, and share thoughts on this paper.
Discussion
Share your thoughts above to start a thread. Constructive feedback only — reply to and like others’ posts.
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0