Nat Med · 2018

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

Jiang P, Gu S, Pan D, Fu J, Sahu A, Hu X, Li Z, Traugh N, Bu X, Li B, Liu J, Freeman GJ, Brown MA, Wucherpfennig KW, Liu XS.

Show affiliations
  • Jiang PDepartment of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Gu SDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Pan DDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Fu JSchool of Life Science and Technology, Tongji University, Shanghai, China.
  • Sahu ADepartment of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Hu XDepartment of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Li ZSchool of Life Science and Technology, Tongji University, Shanghai, China.
  • Traugh NDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Bu XDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Li BDepartment of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Liu JDepartment of Statistics, Harvard University, Cambridge, MA, USA.
  • Freeman GJDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Brown MADepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Wucherpfennig KWDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA. kai_wucherpfennig@dfci.harvard.edu.
  • Liu XSDepartment of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA. xsliu@jimmy.harvard.edu.
4 read3 want to readRigor 2.8Novelty 2.3Impact 3.8Reprod. 3.3

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Yuki Sato

Rigor 3/5Novelty 2/5Impact 5/5Reprod. 5/5

Solid methods, convincing results.