Nature · 2020

Expanded encyclopaedias of DNA elements in the human and mouse genomes

ENCODE Project Consortium, Moore JE, Purcaro MJ, Pratt HE, Epstein CB, Shoresh N, Adrian J, Kawli T, Davis CA, Dobin A, Kaul R, Halow J, Van Nostrand EL, Freese P, Gorkin DU, Shen Y, He Y, Mackiewicz M, Pauli-Behn F, Williams BA, Mortazavi A, Keller CA, Zhang XO, Elhajjajy SI, Huey J, Dickel DE, Snetkova V, Wei X, Wang X, Rivera-Mulia JC, Rozowsky J, Zhang J, Chhetri SB, Zhang J, Victorsen A, White KP, Visel A, Yeo GW, Burge CB, Lécuyer E, Gilbert DM, Dekker J, Rinn J, Mendenhall EM, Ecker JR, Kellis M, Klein RJ, Noble WS, Kundaje A, Guigó R, Farnham PJ, Cherry JM, Myers RM, Ren B, Graveley BR, Gerstein MB, Pennacchio LA, Snyder MP, Bernstein BE, Wold B, Hardison RC, Gingeras TR, Stamatoyannopoulos JA, Weng Z.

Show affiliations
  • Moore JEUniversity of Massachusetts Medical School, Program in Bioinformatics and Integrative Biology, Worcester, MA, USA.
  • Purcaro MJUniversity of Massachusetts Medical School, Program in Bioinformatics and Integrative Biology, Worcester, MA, USA.
  • Pratt HEUniversity of Massachusetts Medical School, Program in Bioinformatics and Integrative Biology, Worcester, MA, USA.
  • Epstein CBThe Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Shoresh NThe Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Adrian JDepartment of Genetics, School of Medicine, Stanford University, Palo Alto, CA, USA.
  • Kawli TDepartment of Genetics, School of Medicine, Stanford University, Palo Alto, CA, USA.
  • Davis CACold Spring Harbor Laboratory, Functional Genomics, Cold Spring Harbor, NY, USA.
  • Dobin ACold Spring Harbor Laboratory, Functional Genomics, Cold Spring Harbor, NY, USA.
  • Kaul RAltius Institute for Biomedical Sciences, Seattle, WA, USA.
  • Halow JAltius Institute for Biomedical Sciences, Seattle, WA, USA.
  • Van Nostrand ELDepartment of Cellular and Molecular Medicine, Institute for Genomic Medicine, Stem Cell Program, Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Freese PProgram in Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Gorkin DUCenter for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Shen YLudwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA, USA.
  • He YGenomics Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
  • Mackiewicz MHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
  • Pauli-Behn FHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
  • Williams BADivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
  • Mortazavi ADepartment of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.
  • Keller CADepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA.
  • Zhang XOUniversity of Massachusetts Medical School, Program in Bioinformatics and Integrative Biology, Worcester, MA, USA.
  • Elhajjajy SIUniversity of Massachusetts Medical School, Program in Bioinformatics and Integrative Biology, Worcester, MA, USA.
  • Huey JUniversity of Massachusetts Medical School, Program in Bioinformatics and Integrative Biology, Worcester, MA, USA.
  • Dickel DEEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
  • Snetkova VEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
  • Wei XDepartment of Genetics and Genome Sciences, Institute for Systems Genomics, UConn Health, Farmington, CT, USA.
  • Wang XDépartement de Biochimie et Médecine Moléculaire, Université de Montréal, Montréal, Quebec, Canada.
  • Rivera-Mulia JCDepartment of Biological Science, Florida State University, Tallahassee, FL, USA.
  • Rozowsky JYale University, New Haven, CT, USA.
  • Zhang JYale University, New Haven, CT, USA.
  • Chhetri SBHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
  • Zhang JDepartment of Genetics, School of Medicine, Yale University, New Haven, CT, USA.
  • Victorsen ADepartment of Human Genetics, Institute for Genomics and Systems Biology, The University of Chicago, Chicago, IL, USA.
  • White KPTempus Labs, Chicago, IL, USA.
  • Visel AEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
  • Yeo GWDepartment of Cellular and Molecular Medicine, Institute for Genomic Medicine, Stem Cell Program, Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Burge CBDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Lécuyer EDépartement de Biochimie et Médecine Moléculaire, Université de Montréal, Montréal, Quebec, Canada.
  • Gilbert DMDepartment of Biological Science, Florida State University, Tallahassee, FL, USA.
  • Dekker JHHMI and Program in Systems Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Rinn JUniversity of Colorado Boulder, Boulder, CO, USA.
  • Mendenhall EMHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
  • Ecker JRGenomics Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
  • Kellis MThe Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Klein RJDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Noble WSDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA.
  • Kundaje ADepartment of Genetics, School of Medicine, Stanford University, Palo Alto, CA, USA.
  • Guigó RBioinformatics and Genomics Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology and Universitat Pompeu Fabra, Barcelona, Spain.
  • Farnham PJDepartment of Biochemistry and Molecular Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Cherry JMDepartment of Genetics, School of Medicine, Stanford University, Palo Alto, CA, USA. cherry@stanford.edu.
  • Myers RMHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA. rmyers@hudsonalpha.org.
  • Ren BCenter for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA. biren@ucsd.edu.
  • Graveley BRDepartment of Genetics and Genome Sciences, Institute for Systems Genomics, UConn Health, Farmington, CT, USA. graveley@uchc.edu.
  • Gerstein MBYale University, New Haven, CT, USA. mark@gersteinlab.org.
  • Pennacchio LAEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. lapennacchio@lbl.gov.
  • Snyder MPDepartment of Genetics, School of Medicine, Stanford University, Palo Alto, CA, USA. mpsnyder@stanford.edu.
  • Bernstein BEBroad Institute and Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Bernstein.Bradley@mgh.harvard.edu.
  • Wold BDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. woldb@caltech.edu.
  • Hardison RCDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA. rch8@psu.edu.
  • Gingeras TRCold Spring Harbor Laboratory, Functional Genomics, Cold Spring Harbor, NY, USA. gingeras@cshl.edu.
  • Stamatoyannopoulos JAAltius Institute for Biomedical Sciences, Seattle, WA, USA. jstam@altius.org.
  • Weng ZUniversity of Massachusetts Medical School, Program in Bioinformatics and Integrative Biology, Worcester, MA, USA. zhiping.weng@umassmed.edu.
66 read9 want to readRigor 3.3Novelty 3.5Impact 3.1Reprod. 3.3

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Discussion

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0

Hugo Silva

Rigor 5/5Novelty 5/5Impact 5/5Reprod. 3/5

Replication is unclear to me.

0

Mei Smith

Rigor 4/5Novelty 2/5Impact 2/5Reprod. 4/5

Solid methods, convincing results.

0

Tariq Nguyen

Rigor 5/5Novelty 4/5Impact 5/5Reprod. 4/5

Great figures and clear story.

0

Tom Nguyen

Rigor 4/5Novelty 5/5Impact 5/5Reprod. 3/5

Important contribution to the field.

0

Lena Rossi

Rigor 4/5Novelty 5/5Impact 5/5Reprod. 1/5

Solid methods, convincing results.

0

Tom Cohen

Rigor 1/5Novelty 5/5Impact 4/5Reprod. 5/5

Interesting idea, small sample.

0

Eva Rossi

Rigor 4/5Novelty 1/5Impact 3/5Reprod. 4/5

Important contribution to the field.

0

Tom Kim

Rigor 1/5Novelty 4/5Impact 1/5Reprod. 4/5

Replication is unclear to me.

0

Tariq Mueller

Rigor 1/5Novelty 2/5Impact 2/5Reprod. 5/5

Interesting idea, small sample.

0

Mei Wang

Rigor 2/5Novelty 1/5Impact 3/5Reprod. 5/5

Important contribution to the field.

0

Sara Garcia

Rigor 5/5Novelty 1/5Impact 2/5Reprod. 3/5

Great figures and clear story.

0

Noor Patel

Rigor 5/5Novelty 3/5Impact 5/5Reprod. 5/5

Interesting idea, small sample.

0

Ines Khan

Rigor 4/5Novelty 2/5Impact 5/5Reprod. 4/5

Replication is unclear to me.

0

Lena Kim

Rigor 4/5Novelty 4/5Impact 3/5Reprod. 1/5

Solid methods, convincing results.

0

Ines Kim

Rigor 2/5Novelty 2/5Impact 3/5Reprod. 3/5

Interesting idea, small sample.

0

Sam Wang

Rigor 4/5Novelty 3/5Impact 4/5Reprod. 1/5

Replication is unclear to me.

0

Pablo Wang

Rigor 4/5Novelty 4/5Impact 4/5Reprod. 1/5

Solid methods, convincing results.

0

Hugo Patel

Rigor 3/5Novelty 4/5Impact 1/5Reprod. 5/5

Replication is unclear to me.

0

Ken Lee

Rigor 1/5Novelty 3/5Impact 3/5Reprod. 3/5

Nice but incremental.

0

Nadia Nguyen

Rigor 3/5Novelty 3/5Impact 3/5Reprod. 4/5

Important contribution to the field.