Nature · 2013

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT.

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  • Heneka MTClinical Neuroscience Unit, Department of Neurology, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany. michael.Heneka@ukb.uni-bonn.de
22 read3 want to readRigor 2.8Novelty 3.1Impact 2.8Reprod. 3.0

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0

Noor Park

Rigor 2/5Novelty 3/5Impact 3/5Reprod. 2/5

Replication is unclear to me.

0

Tariq Park

Rigor 2/5Novelty 1/5Impact 2/5Reprod. 1/5

Important contribution to the field.

0

Yuki Rossi

Rigor 2/5Novelty 1/5Impact 5/5Reprod. 4/5

Great figures and clear story.

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Hugo Mueller

Rigor 5/5Novelty 4/5Impact 2/5Reprod. 4/5

Solid methods, convincing results.

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Lena Patel

Rigor 5/5Novelty 2/5Impact 1/5Reprod. 3/5

Interesting idea, small sample.

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Sara Smith

Rigor 1/5Novelty 2/5Impact 1/5Reprod. 2/5

Replication is unclear to me.