Nature · 2017

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

Hangauer MJ, Viswanathan VS, Ryan MJ, Bole D, Eaton JK, Matov A, Galeas J, Dhruv HD, Berens ME, Schreiber SL, McCormick F, McManus MT.

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Hangauer MJ — Department of Microbiology and Immunology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, California 94143, USA.
Viswanathan VS — Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, USA.
Ryan MJ — Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, USA.
Bole D — UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, 1450 3rd Street, San Francisco, California 94143, USA.
Eaton JK — Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, USA.
Matov A — DataSet Analysis LLC, 155 Jackson Street, San Francisco, California 94111, USA.
Galeas J — UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, 1450 3rd Street, San Francisco, California 94143, USA.
Dhruv HD — Cancer and Cell Biology Division, The Translational Genomics Research Institute, 445 N 5th Street, Phoenix, Arizona 85004, USA.
Berens ME — Cancer and Cell Biology Division, The Translational Genomics Research Institute, 445 N 5th Street, Phoenix, Arizona 85004, USA.
Schreiber SL — Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, USA.
McCormick F — UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, 1450 3rd Street, San Francisco, California 94143, USA.
McManus MT — Department of Microbiology and Immunology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, California 94143, USA.