Alzheimers Dement · 2018

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

Jack CR, Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB, Holtzman DM, Jagust W, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, Rowe CC, Scheltens P, Siemers E, Snyder HM, Sperling R, Contributors.

Show affiliations
  • Jack CR Jr — Department of Radiology, Mayo Clinic, Rochester, MN, USA. Electronic address: jack.clifford@mayo.edu.
  • Bennett DA — Department of Neurological Sciences, Rush University, Chicago, IL, USA.
  • Blennow K — Department of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden.
  • Carrillo MC — Medical & Scientific Relations, Alzheimer's Association, Chicago, IL, USA.
  • Dunn B — Office of Drug Evaluation, FDA, Silver Spring, MD, USA.
  • Haeberlein SB — Biogen, Cambridge, MA, USA.
  • Holtzman DM — Department of Neurology, Washington University, St. Louis, MO, USA.
  • Jagust W — Department of Public Health and Neuroscience, University of California Berkeley, Berkeley, CA, USA.
  • Jessen F — Department of Psychiatry, University of Cologne, Medical Faculty, Cologne, Germany.
  • Karlawish J — Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Liu E — Prothena Biosciences, Inc., San Francisco, CA, USA.
  • Molinuevo JL — BarcelonaBeta Brain Research Center, Pasqual Maragall Foundation and Hospital Clinic-IDIBAPS, Barcelona, Spain.
  • Montine T — Department of Pathology, Stanford University, Standford, CA, USA.
  • Phelps C — Formerly at National Institute on Aging, Bethesda, MD, USA.
  • Rankin KP — Department of Neurology, University of California San Francisco, San Francisco, CA, USA.
  • Rowe CC — Department of Molecular Imaging, Austin Health, University of Melbourne, Melbourne, Australia.
  • Scheltens P — Department of Neurology, VU University Medical Center, Amsterdam, Netherlands.
  • Siemers E — Formerly at Eli Lilly and Company, Indianapolis, IN, USA.
  • Snyder HM — Medical & Scientific Relations, Alzheimer's Association, Chicago, IL, USA.
  • Sperling R — Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA.
22 read2 want to readRigor 3.0Novelty 2.6Impact 2.8Reprod. 2.3

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0

Yuki Brown

Rigor 2/5Novelty 2/5Impact 4/5Reprod. 3/5

Nice but incremental.

0

Ines Brown

Rigor 3/5Novelty 4/5Impact 2/5Reprod. 1/5

Nice but incremental.

0

Sara Silva

Rigor 1/5Novelty 5/5Impact 2/5Reprod. 1/5

Interesting idea, small sample.

0

Pablo Cohen

Rigor 1/5Novelty 1/5Impact 1/5Reprod. 3/5

Great figures and clear story.

0

Jonas Lee

Rigor 3/5Novelty 1/5Impact 4/5Reprod. 1/5

Replication is unclear to me.

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Tom Sato

Rigor 4/5Novelty 4/5Impact 5/5Reprod. 5/5

Replication is unclear to me.