Alzheimers Dement · 2018

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

Jack CR, Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB, Holtzman DM, Jagust W, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, Rowe CC, Scheltens P, Siemers E, Snyder HM, Sperling R, Contributors.

Show affiliations
  • Jack CR JrDepartment of Radiology, Mayo Clinic, Rochester, MN, USA. Electronic address: jack.clifford@mayo.edu.
  • Bennett DADepartment of Neurological Sciences, Rush University, Chicago, IL, USA.
  • Blennow KDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden.
  • Carrillo MCMedical & Scientific Relations, Alzheimer's Association, Chicago, IL, USA.
  • Dunn BOffice of Drug Evaluation, FDA, Silver Spring, MD, USA.
  • Haeberlein SBBiogen, Cambridge, MA, USA.
  • Holtzman DMDepartment of Neurology, Washington University, St. Louis, MO, USA.
  • Jagust WDepartment of Public Health and Neuroscience, University of California Berkeley, Berkeley, CA, USA.
  • Jessen FDepartment of Psychiatry, University of Cologne, Medical Faculty, Cologne, Germany.
  • Karlawish JDepartment of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Liu EProthena Biosciences, Inc., San Francisco, CA, USA.
  • Molinuevo JLBarcelonaBeta Brain Research Center, Pasqual Maragall Foundation and Hospital Clinic-IDIBAPS, Barcelona, Spain.
  • Montine TDepartment of Pathology, Stanford University, Standford, CA, USA.
  • Phelps CFormerly at National Institute on Aging, Bethesda, MD, USA.
  • Rankin KPDepartment of Neurology, University of California San Francisco, San Francisco, CA, USA.
  • Rowe CCDepartment of Molecular Imaging, Austin Health, University of Melbourne, Melbourne, Australia.
  • Scheltens PDepartment of Neurology, VU University Medical Center, Amsterdam, Netherlands.
  • Siemers EFormerly at Eli Lilly and Company, Indianapolis, IN, USA.
  • Snyder HMMedical & Scientific Relations, Alzheimer's Association, Chicago, IL, USA.
  • Sperling RDepartment of Neurology, Brigham and Women's Hospital, Boston, MA, USA.
22 read2 want to readRigor 3.0Novelty 2.6Impact 2.8Reprod. 2.3

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0

Yuki Brown

Rigor 2/5Novelty 2/5Impact 4/5Reprod. 3/5

Nice but incremental.

0

Ines Brown

Rigor 3/5Novelty 4/5Impact 2/5Reprod. 1/5

Nice but incremental.

0

Sara Silva

Rigor 1/5Novelty 5/5Impact 2/5Reprod. 1/5

Interesting idea, small sample.

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Pablo Cohen

Rigor 1/5Novelty 1/5Impact 1/5Reprod. 3/5

Great figures and clear story.

0

Jonas Lee

Rigor 3/5Novelty 1/5Impact 4/5Reprod. 1/5

Replication is unclear to me.

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Tom Sato

Rigor 4/5Novelty 4/5Impact 5/5Reprod. 5/5

Replication is unclear to me.