Nat Med · 2018

Understanding the tumor immune microenvironment (TIME) for effective therapy

Binnewies M, Roberts EW, Kersten K, Chan V, Fearon DF, Merad M, Coussens LM, Gabrilovich DI, Ostrand-Rosenberg S, Hedrick CC, Vonderheide RH, Pittet MJ, Jain RK, Zou W, Howcroft TK, Woodhouse EC, Weinberg RA, Krummel MF.

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Binnewies M — Department of Pathology, University of California, San Francisco, San Francisco, CA, USA.
Roberts EW — Department of Pathology, University of California, San Francisco, San Francisco, CA, USA.
Kersten K — Department of Pathology, University of California, San Francisco, San Francisco, CA, USA.
Chan V — UCSF Immunoprofiler Initiative, University of California, San Francisco, San Francisco, CA, USA.
Fearon DF — Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Merad M — Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Coussens LM — Department of Cell, Developmental & Cancer Biology, Oregon Health and Science University, Portland, OR, USA.
Gabrilovich DI — The Wistar Institute, Philadelphia, PA, USA.
Ostrand-Rosenberg S — Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, MD, USA.
Hedrick CC — Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA.
Vonderheide RH — Department of Medicine, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.
Pittet MJ — Center for Systems Biology, Massachusetts General Hospital, Boston, MA, USA.
Jain RK — Edwin L. Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Zou W — Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI, USA.
Howcroft TK — Division of Cancer Biology, NCI, NIH, Bethesda, MD, USA.
Woodhouse EC — Division of Cancer Biology, NCI, NIH, Bethesda, MD, USA.
Weinberg RA — Whitehead Institute for Biomedical Research, Cambridge, MA, USA. weinberg@wi.mit.edu.
Krummel MF — Department of Pathology, University of California, San Francisco, San Francisco, CA, USA. matthew.krummel@ucsf.edu.