Nat Rev Gastroenterol Hepatol · 2020

Cholangiocarcinoma 2020: the next horizon in mechanisms and management

Banales JM, Marin JJG, Lamarca A, Rodrigues PM, Khan SA, Roberts LR, Cardinale V, Carpino G, Andersen JB, Braconi C, Calvisi DF, Perugorria MJ, Fabris L, Boulter L, Macias RIR, Gaudio E, Alvaro D, Gradilone SA, Strazzabosco M, Marzioni M, Coulouarn C, Fouassier L, Raggi C, Invernizzi P, Mertens JC, Moncsek A, Ilyas SI, Heimbach J, Koerkamp BG, Bruix J, Forner A, Bridgewater J, Valle JW, Gores GJ.

Show affiliations
  • Banales JMDepartment of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital, University of the Basque Country (UPV/EHU), San Sebastian, Spain. jesus.banales@biodonostia.org.
  • Marin JJGNational Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Instituto de Salud Carlos III"), San Sebastian, Spain.
  • Lamarca ADepartment of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
  • Rodrigues PMDepartment of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital, University of the Basque Country (UPV/EHU), San Sebastian, Spain.
  • Khan SADepartment of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK.
  • Roberts LRDivision of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
  • Cardinale VDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy.
  • Carpino GDepartment of Movement, Human and Health Sciences, Division of Health Sciences, University of Rome "Foro Italico", Rome, Italy.
  • Andersen JBBiotech Research and Innovation Centre (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Braconi CInstitute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Calvisi DFInstitute of Pathology, University of Regensburg, Regensburg, Germany.
  • Perugorria MJDepartment of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital, University of the Basque Country (UPV/EHU), San Sebastian, Spain.
  • Fabris LDepartment of Molecular Medicine, University of Padua School of Medicine, Padua, Italy.
  • Boulter LMRC-Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
  • Macias RIRNational Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Instituto de Salud Carlos III"), San Sebastian, Spain.
  • Gaudio EDivision of Human Anatomy, Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences, Sapienza University of Rome, Rome, Italy.
  • Alvaro DDepartment of Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy.
  • Gradilone SAThe Hormel Institute, University of Minnesota, Austin, MN, USA.
  • Strazzabosco MDepartment of Molecular Medicine, University of Padua School of Medicine, Padua, Italy.
  • Marzioni MClinic of Gastroenterology and Hepatology, Universita Politecnica delle Marche, Ancona, Italy.
  • Coulouarn CINSERM, Université de Rennes, Rennes, France.
  • Fouassier LSorbonne Université, INSERM, Centre de Recherche Saint-Antoine (CRSA), Paris, France.
  • Raggi CDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Invernizzi PDivision of Gastroenterology and Center of Autoimmune Liver Diseases, Department of Medicine and Surgery, San Gerardo Hospital, University of Milano, Bicocca, Italy.
  • Mertens JCDepartment of Gastroenterology and Hepatology, University Hospital Zurich and University of Zurich, Zürich, Switzerland.
  • Moncsek ADepartment of Gastroenterology and Hepatology, University Hospital Zurich and University of Zurich, Zürich, Switzerland.
  • Ilyas SIDivision of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
  • Heimbach JDepartment of Surgery, Mayo Clinic, Rochester, MN, USA.
  • Koerkamp BGDepartment of Surgery, Erasmus Medical Center, Rotterdam, Netherlands.
  • Bruix JNational Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Instituto de Salud Carlos III"), San Sebastian, Spain.
  • Forner ANational Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Instituto de Salud Carlos III"), San Sebastian, Spain.
  • Bridgewater JDepartment of Medical Oncology, UCL Cancer Institute, London, UK.
  • Valle JWDepartment of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
  • Gores GJDivision of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
47 read4 want to readRigor 2.9Novelty 2.9Impact 3.3Reprod. 3.3

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Discussion

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0

Sam Patel

Rigor 4/5Novelty 1/5Impact 1/5Reprod. 5/5

Important contribution to the field.

0

Jonas Lee

Rigor 1/5Novelty 3/5Impact 3/5Reprod. 2/5

Great figures and clear story.

0

Hugo Park

Rigor 3/5Novelty 2/5Impact 3/5Reprod. 2/5

Great figures and clear story.

0

Nadia Cohen

Rigor 4/5Novelty 2/5Impact 2/5Reprod. 4/5

Replication is unclear to me.

0

Eva Cohen

Rigor 4/5Novelty 2/5Impact 5/5Reprod. 3/5

Interesting idea, small sample.

0

Hugo Smith

Rigor 3/5Novelty 5/5Impact 3/5Reprod. 4/5

Replication is unclear to me.

0

Eva Wang

Rigor 5/5Novelty 2/5Impact 2/5Reprod. 3/5

Nice but incremental.

0

Noor Brown

Rigor 4/5Novelty 3/5Impact 5/5Reprod. 4/5

Great figures and clear story.

0

Ken Smith

Rigor 2/5Novelty 1/5Impact 5/5Reprod. 5/5

Nice but incremental.

0

Omar Lee

Rigor 1/5Novelty 1/5Impact 5/5Reprod. 2/5

Great figures and clear story.