Nature · 2019

Single-cell transcriptomic analysis of Alzheimer's disease

Mathys H, Davila-Velderrain J, Peng Z, Gao F, Mohammadi S, Young JZ, Menon M, He L, Abdurrob F, Jiang X, Martorell AJ, Ransohoff RM, Hafler BP, Bennett DA, Kellis M, Tsai LH.

Show affiliations
  • Mathys HPicower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Davila-Velderrain JMIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA.
  • Peng ZPicower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Gao FPicower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Mohammadi SMIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA.
  • Young JZPicower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Menon MBroad Institute of MIT and Harvard, Cambridge, MA, USA.
  • He LMIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA.
  • Abdurrob FPicower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Jiang XPicower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Martorell AJPicower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Ransohoff RMThird Rock Ventures, Boston, MA, USA.
  • Hafler BPBroad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Bennett DARush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
  • Kellis MMIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA. manoli@mit.edu.
  • Tsai LHPicower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA. lhtsai@mit.edu.
45 read6 want to readRigor 3.3Novelty 3.2Impact 3.2Reprod. 3.1

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0

Mei Nguyen

Rigor 5/5Novelty 4/5Impact 1/5Reprod. 2/5

Replication is unclear to me.

0

Alex Cohen

Rigor 5/5Novelty 4/5Impact 1/5Reprod. 2/5

Interesting idea, small sample.

0

Mei Kim

Rigor 3/5Novelty 4/5Impact 5/5Reprod. 4/5

Great figures and clear story.

0

Omar Mueller

Rigor 2/5Novelty 1/5Impact 5/5Reprod. 3/5

Interesting idea, small sample.

0

Lena Wang

Rigor 2/5Novelty 5/5Impact 3/5Reprod. 1/5

Solid methods, convincing results.

0

Ravi Mueller

Rigor 3/5Novelty 2/5Impact 4/5Reprod. 1/5

Replication is unclear to me.

0

Sara Khan

Rigor 1/5Novelty 2/5Impact 3/5Reprod. 1/5

Interesting idea, small sample.

0

Ines Park

Rigor 3/5Novelty 5/5Impact 2/5Reprod. 2/5

Important contribution to the field.