Nature · 2017

Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection

Eyquem J, Mansilla-Soto J, Giavridis T, van der Stegen SJ, Hamieh M, Cunanan KM, Odak A, Gönen M, Sadelain M.

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Eyquem J — Center for Cell Engineering and Immunology Program, Sloan Kettering Institute, New York, New York 10065, USA.
Mansilla-Soto J — Center for Cell Engineering and Immunology Program, Sloan Kettering Institute, New York, New York 10065, USA.
Giavridis T — Center for Cell Engineering and Immunology Program, Sloan Kettering Institute, New York, New York 10065, USA.
van der Stegen SJ — Center for Cell Engineering and Immunology Program, Sloan Kettering Institute, New York, New York 10065, USA.
Hamieh M — Center for Cell Engineering and Immunology Program, Sloan Kettering Institute, New York, New York 10065, USA.
Cunanan KM — Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
Odak A — Center for Cell Engineering and Immunology Program, Sloan Kettering Institute, New York, New York 10065, USA.
Gönen M — Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
Sadelain M — Center for Cell Engineering and Immunology Program, Sloan Kettering Institute, New York, New York 10065, USA.