Cell · 2013

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, Zhang F, Jaenisch R.

Show affiliations
  • Wang H — Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
Open on PubMed ↗Open at publisher ↗PMID 23643243
35 read3 want to readRigor 3.2Novelty 3.3Impact 3.2Reprod. 2.9

Most-cited papers citing this

  • J Hematol Oncol · 2025 · cited by 15
  • Nature · 2025 · cited by 12
  • BioTech (Basel) · 2025 · cited by 10
  • Small · 2026 · cited by 9
  • Mol Ther · 2025 · cited by 9

Log in to like, log, and share thoughts on this paper.

Discussion

Share your thoughts above to start a thread. Constructive feedback only — reply to and like others’ posts.

0

Eva Sato

Rigor 1/5Novelty 3/5Impact 1/5Reprod. 1/5

Great figures and clear story.

0

Noor Cohen

Rigor 2/5Novelty 5/5Impact 3/5Reprod. 5/5

Interesting idea, small sample.

0

Pablo Garcia

Rigor 3/5Novelty 5/5Impact 4/5Reprod. 5/5

Solid methods, convincing results.

0

Tariq Sato

Rigor 5/5Novelty 2/5Impact 3/5Reprod. 2/5

Important contribution to the field.

0

Ines Khan

Rigor 5/5Novelty 2/5Impact 4/5Reprod. 1/5

Solid methods, convincing results.

0

Liam Patel

Rigor 2/5Novelty 4/5Impact 4/5Reprod. 1/5

Nice but incremental.

0

Lena Patel

Rigor 1/5Novelty 4/5Impact 4/5Reprod. 5/5

Solid methods, convincing results.

0

Jonas Silva

Rigor 3/5Novelty 4/5Impact 5/5Reprod. 4/5

Nice but incremental.

0

Sara Silva

Rigor 3/5Novelty 4/5Impact 5/5Reprod. 3/5

Interesting idea, small sample.