Cell · 2013

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA.

Show affiliations
  • Qi LS — UCSF Center for Systems and Synthetic Biology, University of California, San Francisco, San Francisco, CA 94158, USA. stanley.qi@ucsf.edu
Open on PubMed ↗Open at publisher ↗PMID 23452860
36 read7 want to readRigor 2.9Novelty 3.2Impact 2.8Reprod. 2.9

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Tom Sato

Rigor 4/5Novelty 1/5Impact 5/5Reprod. 3/5

Solid methods, convincing results.

0

Jonas Wang

Rigor 1/5Novelty 1/5Impact 2/5Reprod. 1/5

Interesting idea, small sample.

0

Mei Mueller

Rigor 3/5Novelty 5/5Impact 1/5Reprod. 5/5

Solid methods, convincing results.

0

Nadia Garcia

Rigor 4/5Novelty 3/5Impact 3/5Reprod. 1/5

Replication is unclear to me.

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Hugo Khan

Rigor 3/5Novelty 4/5Impact 1/5Reprod. 4/5

Nice but incremental.

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Pablo Nguyen

Rigor 1/5Novelty 4/5Impact 4/5Reprod. 4/5

Important contribution to the field.

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Liam Lee

Rigor 3/5Novelty 4/5Impact 2/5Reprod. 1/5

Important contribution to the field.