Nature · 2012

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

Curtis C, Shah SP, Chin SF, Turashvili G, Rueda OM, Dunning MJ, Speed D, Lynch AG, Samarajiwa S, Yuan Y, Gräf S, Ha G, Haffari G, Bashashati A, Russell R, McKinney S, METABRIC Group, Langerød A, Green A, Provenzano E, Wishart G, Pinder S, Watson P, Markowetz F, Murphy L, Ellis I, Purushotham A, Børresen-Dale AL, Brenton JD, Tavaré S, Caldas C, Aparicio S.

Show affiliations
  • Curtis CDepartment of Oncology, University of Cambridge, Hills Road, Cambridge CB2 2XZ, UK.
66 read7 want to readRigor 3.2Novelty 2.8Impact 3.1Reprod. 3.0

Most-cited papers citing this

  • Nat Immunol · 2026 · cited by 3
  • Nat Biomed Eng · 2026 · cited by 2
  • Nat Immunol · 2026 · cited by 2
  • Nat Genet · 2026 · cited by 2
  • Cell Rep · 2025 · cited by 2

Log in to like, log, and share thoughts on this paper.

Discussion

Share your thoughts above to start a thread. Constructive feedback only — reply to and like others’ posts.

0

Eva Rossi

Rigor 4/5Novelty 2/5Impact 5/5Reprod. 4/5

Replication is unclear to me.

0

Maya Wang

Rigor 3/5Novelty 3/5Impact 2/5Reprod. 3/5

Great figures and clear story.

0

Ken Wang

Rigor 5/5Novelty 1/5Impact 4/5Reprod. 5/5

Important contribution to the field.

0

Alex Garcia

Rigor 4/5Novelty 2/5Impact 5/5Reprod. 3/5

Solid methods, convincing results.

0

Omar Brown

Rigor 5/5Novelty 1/5Impact 3/5Reprod. 1/5

Solid methods, convincing results.

0

Ravi Sato

Rigor 1/5Novelty 3/5Impact 1/5Reprod. 1/5

Interesting idea, small sample.

0

Hugo Nguyen

Rigor 2/5Novelty 4/5Impact 3/5Reprod. 2/5

Nice but incremental.

0

Hugo Silva

Rigor 3/5Novelty 3/5Impact 3/5Reprod. 4/5

Solid methods, convincing results.

0

Omar Kim

Rigor 2/5Novelty 2/5Impact 5/5Reprod. 4/5

Great figures and clear story.

0

Sam Kim

Rigor 2/5Novelty 3/5Impact 1/5Reprod. 3/5

Great figures and clear story.

0

Ken Mueller

Rigor 2/5Novelty 3/5Impact 3/5Reprod. 3/5

Solid methods, convincing results.

0

Sara Mueller

Rigor 2/5Novelty 5/5Impact 4/5Reprod. 4/5

Replication is unclear to me.

0

Jonas Patel

Rigor 5/5Novelty 3/5Impact 3/5Reprod. 5/5

Solid methods, convincing results.

0

Ines Lee

Rigor 2/5Novelty 3/5Impact 3/5Reprod. 2/5

Replication is unclear to me.

0

Alex Khan

Rigor 1/5Novelty 5/5Impact 2/5Reprod. 4/5

Nice but incremental.

0

Sam Nguyen

Rigor 5/5Novelty 2/5Impact 5/5Reprod. 1/5

Replication is unclear to me.