Nat Rev Neurol · 2018

Blood-brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

Sweeney MD, Sagare AP, Zlokovic BV.

Show affiliations
  • Sweeney MD — Department of Physiology and Neuroscience and the Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, 1501 San Pablo Street, Los Angeles, California 90089, USA.
  • Sagare AP — Department of Physiology and Neuroscience and the Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, 1501 San Pablo Street, Los Angeles, California 90089, USA.
  • Zlokovic BV — Department of Physiology and Neuroscience and the Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, 1501 San Pablo Street, Los Angeles, California 90089, USA.
45 read5 want to readRigor 3.2Novelty 3.0Impact 2.7Reprod. 2.8

Most-cited papers citing this

  • Nat Aging · 2026 · cited by 1
  • Geroscience · 2026 · cited by 1
  • Mech Ageing Dev · 2026 · cited by 1
  • Adv Sci (Weinh) · 2026 · cited by 1
  • Alzheimers Dement (N Y) · 2026 · cited by 1

Log in to like, log, and share thoughts on this paper.

Discussion

Share your thoughts above to start a thread. Constructive feedback only — reply to and like others’ posts.

0

Alex Ivanova

Rigor 1/5Novelty 3/5Impact 1/5Reprod. 3/5

Nice but incremental.

0

Pablo Khan

Rigor 2/5Novelty 2/5Impact 2/5Reprod. 3/5

Interesting idea, small sample.

0

Maya Nguyen

Rigor 3/5Novelty 3/5Impact 2/5Reprod. 3/5

Important contribution to the field.

0

Liam Garcia

Rigor 5/5Novelty 1/5Impact 1/5Reprod. 3/5

Important contribution to the field.

0

Liam Sato

Rigor 4/5Novelty 5/5Impact 5/5Reprod. 1/5

Interesting idea, small sample.

0

Alex Cohen

Rigor 1/5Novelty 1/5Impact 1/5Reprod. 3/5

Interesting idea, small sample.

0

Jonas Rossi

Rigor 4/5Novelty 4/5Impact 2/5Reprod. 5/5

Important contribution to the field.

0

Omar Patel

Rigor 3/5Novelty 1/5Impact 1/5Reprod. 2/5

Nice but incremental.

0

Lena Patel

Rigor 5/5Novelty 2/5Impact 4/5Reprod. 2/5

Great figures and clear story.

0

Ravi Silva

Rigor 3/5Novelty 1/5Impact 4/5Reprod. 4/5

Interesting idea, small sample.

0

Pablo Lee

Rigor 5/5Novelty 5/5Impact 2/5Reprod. 1/5

Great figures and clear story.