Science · 2014

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

Doudna JA, Charpentier E.

Show affiliations
  • Doudna JAHoward Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA. Department of Chemistry, University of California, Berkeley, CA 94720, USA. Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. doudna@berkeley.edu emmanuelle.charpentier@helmholtz-hzi.de.
  • Charpentier EDepartment of Regulation in Infection Biology, Helmholtz Centre for Infection Research, D-38124 Braunschweig, Germany. Laboratory for Molecular Infection Medicine Sweden, Umeå Centre for Microbial Research, Department of Molecular Biology, Umeå University, S-90187 Umeå, Sweden. Hannover Medical School, D-30625 Hannover, Germany. doudna@berkeley.edu emmanuelle.charpentier@helmholtz-hzi.de.
25 read3 want to readRigor 3.1Novelty 3.2Impact 3.1Reprod. 2.5

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0

Nadia Sato

Rigor 3/5Novelty 5/5Impact 5/5Reprod. 5/5

Great figures and clear story.

0

Alex Brown

Rigor 5/5Novelty 4/5Impact 1/5Reprod. 4/5

Important contribution to the field.

0

Ravi Brown

Rigor 4/5Novelty 3/5Impact 5/5Reprod. 2/5

Replication is unclear to me.

0

Sam Rossi

Rigor 2/5Novelty 4/5Impact 1/5Reprod. 4/5

Replication is unclear to me.

0

Hugo Nguyen

Rigor 4/5Novelty 2/5Impact 5/5Reprod. 1/5

Interesting idea, small sample.

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Ravi Kim

Rigor 4/5Novelty 1/5Impact 3/5Reprod. 4/5

Interesting idea, small sample.