Nat Genet · 2022

New insights into the genetic etiology of Alzheimer's disease and related dementias

Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarcón-Martín E, Alcolea D, Alegret M, Alvarez I, Álvarez V, Armstrong NJ, Tsolaki A, Antúnez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Bossù P, Bråthen G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, Bûrger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo Á, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen HH, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-Gómez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues JF, de Deyn PP, de Paiva Lopes K, de Witte LD, Debette S, Deckert J, Del Ser T, Denning N, DeStefano A, Dichgans M, Diehl-Schmid J, Diez-Fairen M, Rossi PD, Djurovic S, Duron E, Düzel E, Dufouil C, Eiriksdottir G, Engelborghs S, Escott-Price V, Espinosa A, Ewers M, Faber KM, Fabrizio T, Nielsen SF, Fardo DW, Farotti L, Fenoglio C, Fernández-Fuertes M, Ferrari R, Ferreira CB, Ferri E, Fin B, Fischer P, Fladby T, Fließbach K, Fongang B, Fornage M, Fortea J, Foroud TM, Fostinelli S, Fox NC, Franco-Macías E, Bullido MJ, Frank-García A, Froelich L, Fulton-Howard B, Galimberti D, García-Alberca JM, García-González P, Garcia-Madrona S, Garcia-Ribas G, Ghidoni R, Giegling I, Giorgio G, Goate AM, Goldhardt O, Gomez-Fonseca D, González-Pérez A, Graff C, Grande G, Green E, Grimmer T, Grünblatt E, Grunin M, Gudnason V, Guetta-Baranes T, Haapasalo A, Hadjigeorgiou G, Haines JL, Hamilton-Nelson KL, Hampel H, Hanon O, Hardy J, Hartmann AM, Hausner L, Harwood J, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herrmann MJ, Hoffmann P, Holmes C, Holstege H, Vilas RH, Hulsman M, Humphrey J, Biessels GJ, Jian X, Johansson C, Jun GR, Kastumata Y, Kauwe J, Kehoe PG, Kilander L, Ståhlbom AK, Kivipelto M, Koivisto A, Kornhuber J, Kosmidis MH, Kukull WA, Kuksa PP, Kunkle BW, Kuzma AB, Lage C, Laukka EJ, Launer L, Lauria A, Lee CY, Lehtisalo J, Lerch O, Lleó A, Longstreth W, Lopez O, de Munain AL, Love S, Löwemark M, Luckcuck L, Lunetta KL, Ma Y, Macías J, MacLeod CA, Maier W, Mangialasche F, Spallazzi M, Marquié M, Marshall R, Martin ER, Montes AM, Rodríguez CM, Masullo C, Mayeux R, Mead S, Mecocci P, Medina M, Meggy A, Mehrabian S, Mendoza S, Menéndez-González M, Mir P, Moebus S, Mol M, Molina-Porcel L, Montrreal L, Morelli L, Moreno F, Morgan K, Mosley T, Nöthen MM, Muchnik C, Mukherjee S, Nacmias B, Ngandu T, Nicolas G, Nordestgaard BG, Olaso R, Orellana A, Orsini M, Ortega G, Padovani A, Paolo C, Papenberg G, Parnetti L, Pasquier F, Pastor P, Peloso G, Pérez-Cordón A, Pérez-Tur J, Pericard P, Peters O, Pijnenburg YAL, Pineda JA, Piñol-Ripoll G, Pisanu C, Polak T, Popp J, Posthuma D, Priller J, Puerta R, Quenez O, Quintela I, Thomassen JQ, Rábano A, Rainero I, Rajabli F, Ramakers I, Real LM, Reinders MJT, Reitz C, Reyes-Dumeyer D, Ridge P, Riedel-Heller S, Riederer P, Roberto N, Rodriguez-Rodriguez E, Rongve A, Allende IR, Rosende-Roca M, Royo JL, Rubino E, Rujescu D, Sáez ME, Sakka P, Saltvedt I, Sanabria Á, Sánchez-Arjona MB, Sanchez-Garcia F, Juan PS, Sánchez-Valle R, Sando SB, Sarnowski C, Satizabal CL, Scamosci M, Scarmeas N, Scarpini E, Scheltens P, Scherbaum N, Scherer M, Schmid M, Schneider A, Schott JM, Selbæk G, Seripa D, Serrano M, Sha J, Shadrin AA, Skrobot O, Slifer S, Snijders GJL, Soininen H, Solfrizzi V, Solomon A, Song Y, Sorbi S, Sotolongo-Grau O, Spalletta G, Spottke A, Squassina A, Stordal E, Tartan JP, Tárraga L, Tesí N, Thalamuthu A, Thomas T, Tosto G, Traykov L, Tremolizzo L, Tybjærg-Hansen A, Uitterlinden A, Ullgren A, Ulstein I, Valero S, Valladares O, Broeckhoven CV, Vance J, Vardarajan BN, van der Lugt A, Dongen JV, van Rooij J, van Swieten J, Vandenberghe R, Verhey F, Vidal JS, Vogelgsang J, Vyhnalek M, Wagner M, Wallon D, Wang LS, Wang R, Weinhold L, Wiltfang J, Windle G, Woods B, Yannakoulia M, Zare H, Zhao Y, Zhang X, Zhu C, Zulaica M, EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC, CHARGE, Farrer LA, Psaty BM, Ghanbari M, Raj T, Sachdev P, Mather K, Jessen F, Ikram MA, de Mendonça A, Hort J, Tsolaki M, Pericak-Vance MA, Amouyel P, Williams J, Frikke-Schmidt R, Clarimon J, Deleuze JF, Rossi G, Seshadri S, Andreassen OA, Ingelsson M, Hiltunen M, Sleegers K, Schellenberg GD, van Duijn CM, Sims R, van der Flier WM, Ruiz A, Ramirez A, Lambert JC.

Show affiliations
  • Bellenguez CUniversité de Lille, INSERM, CHU Lille, Institut Pasteur Lille, U1167-RID-AGE, Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France. celine.bellenguez@pasteur-lille.fr.
  • Küçükali FComplex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.
  • Jansen IEAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Kleineidam LDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
  • Moreno-Grau SResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Amin NDepartment of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.
  • Naj ACDepartment of Biostatistics, Epidemiology, and Informatics, Penn Neurodegeneration Genomics Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Campos-Martin RDivision of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany.
  • Grenier-Boley BUniversité de Lille, INSERM, CHU Lille, Institut Pasteur Lille, U1167-RID-AGE, Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.
  • Andrade VDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
  • Holmans PAMRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.
  • Boland ACEA, Centre National de Recherche en Génomique Humaine, Université Paris-Saclay, Evry, France.
  • Damotte VUniversité de Lille, INSERM, CHU Lille, Institut Pasteur Lille, U1167-RID-AGE, Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.
  • van der Lee SJAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Costa MRUniversité de Lille, INSERM, CHU Lille, Institut Pasteur Lille, U1167-RID-AGE, Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.
  • Kuulasmaa TInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
  • Yang QDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • de Rojas IResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Bis JCCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Yaqub ADepartment of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.
  • Prokic IDepartment of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.
  • Chapuis JUniversité de Lille, INSERM, CHU Lille, Institut Pasteur Lille, U1167-RID-AGE, Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.
  • Ahmad SDepartment of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.
  • Giedraitis VDepartment of Public Health and Carins Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.
  • Aarsland DCentre of Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway.
  • Garcia-Gonzalez PResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Abdelnour CResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Alarcón-Martín EResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Alcolea DCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Alegret MResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Alvarez IFundació Docència i Recerca MútuaTerrassa and Movement Disorders Unit, Department of Neurology, University Hospital MútuaTerrassa, Terrassa, Spain.
  • Álvarez VLaboratorio de Genética, Hospital Universitario Central de Asturias, Oviedo, Spain.
  • Armstrong NJCentre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.
  • Tsolaki AFirst Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Antúnez CUnidad de Demencias, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain.
  • Appollonio ISchool of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy.
  • Arcaro MFondazione IRCCS Ca'Granda, Ospedale Policlinico, Milan, Italy.
  • Archetti SDepartment of Laboratory Diagnostics, III Laboratory of Analysis, Brescia Hospital, Brescia, Italy.
  • Pastor AAUnitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain.
  • Arosio BDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
  • Athanasiu LNORMENT Centre, University of Oslo, Oslo, Norway.
  • Bailly HEA 4468, Université de Paris, APHP, Hôpital Broca, Paris, France.
  • Banaj NLaboratory of Neuropsychiatry, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy.
  • Baquero MServei de Neurologia, Hospital Universitari i Politècnic La Fe, Valencia, Spain.
  • Barral STaub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.
  • Beiser AInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
  • Pastor ABCIEN Foundation/Queen Sofia Foundation Alzheimer Center, Madrid, Spain.
  • Below JEVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA.
  • Benchek PCleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.
  • Benussi LMolecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
  • Berr CNeuropsychiatry: Epidemiological and Clinical Research, PSNREC, Université de Montpellier, INSERM U1061, Montpellier, France.
  • Besse CCEA, Centre National de Recherche en Génomique Humaine, Université Paris-Saclay, Evry, France.
  • Bessi VDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
  • Binetti GMolecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
  • Bizarro AGeriatrics Unit, Fondazione Policlinico A. Gemelli IRCCS, Rome, Italy.
  • Blesa RCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Boada MResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Boerwinkle EHuman Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Borroni BCentre for Neurodegenerative Disorders, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
  • Boschi SDepartment of Neuroscience "Rita Levi Montalcini", University of Torino, Torino, Italy.
  • Bossù PExperimental Neuro-psychobiology Laboratory, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy.
  • Bråthen GDepartment of Neurology and Clinical Neurophysiology, University Hospital of Trondheim, Trondheim, Norway.
  • Bressler JHuman Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Bresner CMRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.
  • Brodaty HCentre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.
  • Brookes KJBiosciences, School of Science and Technology, Nottingham Trent University, Nottingham, UK.
  • Brusco LICentro de Neuropsiquiatría y Neurología de la Conducta (CENECON), Facultad de Medicina, Universidad de Buenos Aires (UBA), C.A.B.A., Buenos Aires, Argentina.
  • Buiza-Rueda DCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Bûrger KInstitute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig Maximilians Universität (LMU), Munich, Germany.
  • Burholt VFaculty of Medical & Health Sciences, University of Auckland, Auckland, New Zealand.
  • Bush WSDepartment of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.
  • Calero MResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Cantwell LBDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Chene GINSERM, Bordeaux Population Health Research Center, UMR 1219, ISPED, CIC 1401-EC, Université de Bordeaux, Bordeaux, France.
  • Chung JMedicine Biomedical Genetics Boston University School of Medicine, Boston, MA, USA.
  • Cuccaro MLDr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, FL, USA.
  • Carracedo ÁGrupo de Medicina Xenómica, Centro Nacional de Genotipado (CEGEN-PRB3-ISCIII), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
  • Cecchetti RInstitute of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Cervera-Carles LCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Charbonnier CDepartment of Genetics and CNR-MAJ, Normandie University, UNIROUEN, INSERM U1245, CHU Rouen, Rouen, France.
  • Chen HHDivision of Genetic Medicine, Vanderbilt University, Nashville, TN, USA.
  • Chillotti CUnit of Clinical Pharmacology, University Hospital of Cagliari, Cagliari, Italy.
  • Ciccone SGeriatic Unit, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy.
  • Claassen JAHRRadboudumc Alzheimer Center, Department of Geriatrics, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Clark CInstitute for Regenerative Medicine, University of Zürich, Schlieren, Switzerland.
  • Conti ESchool of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy.
  • Corma-Gómez AUnidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain.
  • Costantini EDepartment of Neuroscience, Catholic University of Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Custodero CUniversity of Bari, "A. Moro", Bary, Italy.
  • Daian DCEA, Centre National de Recherche en Génomique Humaine, Université Paris-Saclay, Evry, France.
  • Dalmasso MCDivision of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany.
  • Daniele ADepartment of Neuroscience, Catholic University of Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Dardiotis ESchool of Medicine, University of Thessaly, Larissa, Greece.
  • Dartigues JFBordeaux Population Health Research Center, University Bordeaux, INSERM, Bordeaux, France.
  • de Deyn PPDepartment of Neurology, University Medical Center Groningen, Groningen, the Netherlands.
  • de Paiva Lopes KRonald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • de Witte LDDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Debette SBordeaux Population Health Research Center, University Bordeaux, INSERM, Bordeaux, France.
  • Deckert JDepartment of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital, Wuerzburg, Germany.
  • Del Ser TCIEN Foundation/Queen Sofia Foundation Alzheimer Center, Madrid, Spain.
  • Denning NUKDRI@ Cardiff, School of Medicine, Cardiff University, Cardiff, UK.
  • DeStefano AInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
  • Dichgans MInstitute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig Maximilians Universität (LMU), Munich, Germany.
  • Diehl-Schmid JKlinikum rechts der Isar, Department of Psychiatry and Psychotherapy, Technical University of Munich, School of Medicine, Munich, Germany.
  • Diez-Fairen MFundació Docència i Recerca MútuaTerrassa and Movement Disorders Unit, Department of Neurology, University Hospital MútuaTerrassa, Terrassa, Spain.
  • Rossi PDGeriatic Unit, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy.
  • Djurovic SNORMENT Centre, University of Oslo, Oslo, Norway.
  • Duron EEA 4468, Université de Paris, APHP, Hôpital Broca, Paris, France.
  • Düzel EInstitute of Cognitive Neurology and Dementia Research (IKND), Otto-Von-Guericke University, Magdeburg, Germany.
  • Dufouil CINSERM, Bordeaux Population Health Research Center, UMR 1219, ISPED, CIC 1401-EC, Université de Bordeaux, Bordeaux, France.
  • Eiriksdottir GIcelandic Heart Association, Kopovagur, Iceland.
  • Engelborghs SCenter for Neurosciences, Vrije Universiteit Brussel (VUB), Brussels, Belgium.
  • Escott-Price VDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Espinosa AResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Ewers MInstitute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig Maximilians Universität (LMU), Munich, Germany.
  • Faber KMDepartment of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA.
  • Fabrizio TFondazione IRCCS, Istituto Neurologico Carlo Besta, Milan, Italy.
  • Nielsen SFDepartment of Clinical Biochemistry, Herlev and Gentofte Hospital, Herlev, Denmark.
  • Fardo DWSanders-Brown Center on Aging, Department of Biostatistics, University of Kentucky, Lexington, KY, USA.
  • Farotti LCentre for Memory Disturbances, Lab of Clinical Neurochemistry, Section of Neurology, University of Perugia, Perugia, Italy.
  • Fenoglio CUniversity of Milan, Milan, Italy.
  • Fernández-Fuertes MUnidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain.
  • Ferrari RLaboratory of Neurogenetics, Department of Internal Medicine, Texas Tech University Health Science Center, Lubbock, TX, USA.
  • Ferreira CBFaculty of Medicine, University of Lisbon, Lisbon, Portugal.
  • Ferri EGeriatic Unit, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy.
  • Fin BCEA, Centre National de Recherche en Génomique Humaine, Université Paris-Saclay, Evry, France.
  • Fischer PDepartment of Psychiatry, Social Medicine Center East- Donauspital, Vienna, Austria.
  • Fladby TInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Fließbach KDivision of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany.
  • Fongang BGlenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, USA.
  • Fornage MDepartment of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.
  • Fortea JCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Foroud TMDepartment of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA.
  • Fostinelli SMolecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
  • Fox NCDementia Research Centre, UCL Queen Square Institute of Neurology, London, UK.
  • Franco-Macías EUnidad de Demencias, Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.
  • Bullido MJCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Frank-García ACIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Froelich LDepartment of Geriatric Psychiatry, Central Institute for Mental Health, Mannheim, University of Heidelberg, Heidelberg, Germany.
  • Fulton-Howard BDepartment of Genetics and Genomic Sciences, Ronald M. Loeb Center for Alzheimer's Disease Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Galimberti DFondazione IRCCS Ca'Granda, Ospedale Policlinico, Milan, Italy.
  • García-Alberca JMCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • García-González PResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Garcia-Madrona SHospital Universitario Ramon y Cajal, IRYCIS, Madrid, Spain.
  • Garcia-Ribas GHospital Universitario Ramon y Cajal, IRYCIS, Madrid, Spain.
  • Ghidoni RMolecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
  • Giegling IDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
  • Giorgio GFondazione IRCCS, Istituto Neurologico Carlo Besta, Milan, Italy.
  • Goate AMDepartment of Genetics and Genomic Sciences, Ronald M. Loeb Center for Alzheimer's Disease Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Goldhardt OKlinikum rechts der Isar, Department of Psychiatry and Psychotherapy, Technical University of Munich, School of Medicine, Munich, Germany.
  • Gomez-Fonseca DDepartment of Biostatistics, Epidemiology, and Informatics Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • González-Pérez ACAEBI, Centro Andaluz de Estudios Bioinformáticos, Sevilla, Spain.
  • Graff CCenter for Alzheimer Research, Department NVS, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden.
  • Grande GAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
  • Green EInstitute of Public Health, University of Cambridge, Cambridge, UK.
  • Grimmer TKlinikum rechts der Isar, Department of Psychiatry and Psychotherapy, Technical University of Munich, School of Medicine, Munich, Germany.
  • Grünblatt EDepartment of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland.
  • Grunin MDepartment of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.
  • Gudnason VIcelandic Heart Association, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
  • Guetta-Baranes THuman Genetics, School of Life Sciences, Life Sciences Building, University Park, University of Nottingham, Nottingham, UK.
  • Haapasalo AAI Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
  • Hadjigeorgiou GDepartment of Neurology, Medical School, University of Cyprus, Nicosia, Cyprus.
  • Haines JLDepartment of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.
  • Hamilton-Nelson KLThe John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.
  • Hampel HGRC 21, Alzheimer Precision Medicine Initiative (APMI), Sorbonne University, AP-HP, Pitié-Salpêtrière Hospital, Paris, France.
  • Hanon OEA 4468, Université de Paris, APHP, Hôpital Broca, Paris, France.
  • Hardy JReta Lila Weston Research Laboratories, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
  • Hartmann AMDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
  • Hausner LDepartment of Geriatric Psychiatry, Central Institute for Mental Health, Mannheim, University of Heidelberg, Heidelberg, Germany.
  • Harwood JMRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.
  • Heilmann-Heimbach SInstitute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.
  • Helisalmi SInstitute of Clinical Medicine, Neurology, University of Eastern, Kuopio, Finland.
  • Heneka MTDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
  • Hernández IResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Herrmann MJDepartment of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital, Wuerzburg, Germany.
  • Hoffmann PInstitute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.
  • Holmes CClinical and Experimental Science, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Holstege HAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Vilas RHUnitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain.
  • Hulsman MAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Humphrey JRonald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Biessels GJDepartment of Neurology, UMC Utrecht Brain Center, Utrecht, the Netherlands.
  • Jian XGlenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, USA.
  • Johansson CCenter for Alzheimer Research, Department NVS, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden.
  • Jun GRMedicine Biomedical Genetics Boston University School of Medicine, Boston, MA, USA.
  • Kastumata YBiostatistics, University of Kentucky College of Public Health, Lexington, KY, USA.
  • Kauwe JDepartment of Biology, Brigham Young University, Provo, UT, USA.
  • Kehoe PGTranslational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Kilander LDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • Ståhlbom AKCenter for Alzheimer Research, Department NVS, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden.
  • Kivipelto MDivision of Clinical Geriatrics, Center for Alzheimer Research, Care Sciences and Society (NVS), Karolinska Institutet, Stockholm, Sweden.
  • Koivisto AInstitute of Clinical Medicine, Neurology, University of Eastern, Kuopio, Finland.
  • Kornhuber JDepartment of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.
  • Kosmidis MHLaboratory of Cognitive Neuroscience, School of Psychology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Kukull WADepartment of Epidemiology, University of Washington, Seattle, WA, USA.
  • Kuksa PPDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
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  • Lage CCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Laukka EJAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
  • Launer LLaboratory of Epidemiology, Demography, and Biometry, National Institute of Aging, The National Institutes of Health, Bethesda, MD, USA.
  • Lauria AGeriatrics Unit, Fondazione Policlinico A. Gemelli IRCCS, Rome, Italy.
  • Lee CYDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Lehtisalo JInstitute of Clinical Medicine, Neurology, University of Eastern, Kuopio, Finland.
  • Lerch OMemory Clinic, Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Praha, Czechia.
  • Lleó ACIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Longstreth W JrDepartments of Neurology and Epidemiology, University of Washington, Seattle, WA, USA.
  • Lopez OFramingham Heart Study, Framingham, MA, USA.
  • de Munain ALCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Love STranslational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Löwemark MDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • Luckcuck LMRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.
  • Lunetta KLInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
  • Ma YSection Genomics of Neurodegenerative Diseases and Aging, Department of Human Genetics Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Macías JUnidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain.
  • MacLeod CASchool of Health Sciences, Bangor University, Bangor, UK.
  • Maier WDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
  • Mangialasche FDivision of Clinical Geriatrics, Center for Alzheimer Research, Care Sciences and Society (NVS), Karolinska Institutet, Stockholm, Sweden.
  • Spallazzi MUnit of Neurology, University of Parma and AOU, Parma, Italy.
  • Marquié MResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Marshall RMRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.
  • Martin ERThe John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.
  • Montes AMCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Rodríguez CMServicio de Neurología, Hospital Universitario Central de Asturias- Oviedo and Instituto de Investigación Biosanitaria del Principado de Asturias, Oviedo, Spain.
  • Masullo CInstitute of Neurology, Catholic University of the Sacred Heart, Rome, Italy.
  • Mayeux RTaub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.
  • Mead SMRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, UK.
  • Mecocci PInstitute of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Medina MCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Meggy AUKDRI@ Cardiff, School of Medicine, Cardiff University, Cardiff, UK.
  • Mehrabian SClinic of Neurology, UH 'Alexandrovska', Medical University - Sofia, Sofia, Bulgaria.
  • Mendoza SAlzheimer Research Center & Memory Clinic, Andalusian Institute for Neuroscience, Málaga, Spain.
  • Menéndez-González MServicio de Neurología, Hospital Universitario Central de Asturias- Oviedo and Instituto de Investigación Biosanitaria del Principado de Asturias, Oviedo, Spain.
  • Mir PCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Moebus SInstitute for Urban Public Health, University Hospital of University Duisburg-Essen, Essen, Germany.
  • Mol MDepartment of Neurology, Erasmus MC, Rotterdam, the Netherlands.
  • Molina-Porcel LNeurological Tissue Bank of the Biobanc-Hospital Clinic-IDIBAPS, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
  • Montrreal LResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Morelli LLaboratory of Brain Aging and Neurodegeneration, FIL-CONICET, Buenos Aires, Argentina.
  • Moreno FCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Morgan KHuman Genetics, School of Life Sciences, University of Nottingham, Nottingham, UK.
  • Mosley TMemory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS, USA.
  • Nöthen MMInstitute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.
  • Muchnik CCentro de Neuropsiquiatría y Neurología de la Conducta (CENECON), Facultad de Medicina, Universidad de Buenos Aires (UBA), C.A.B.A., Buenos Aires, Argentina.
  • Mukherjee SDepartment of Medicine, University of Washington, Seattle, WA, USA.
  • Nacmias BDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
  • Ngandu TPublic Health Promotion Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.
  • Nicolas GDepartment of Genetics and CNR-MAJ, Normandie University, UNIROUEN, INSERM U1245, CHU Rouen, Rouen, France.
  • Nordestgaard BGDepartment of Clinical Biochemistry, Herlev and Gentofte Hospital, Herlev, Denmark.
  • Olaso RCEA, Centre National de Recherche en Génomique Humaine, Université Paris-Saclay, Evry, France.
  • Orellana AResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Orsini MDepartment of Neuroscience, Catholic University of Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Ortega GResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Padovani AHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
  • Paolo CDIMEC, University of Parma, Parma, Italy.
  • Papenberg GAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
  • Parnetti LCentre for Memory Disturbances, Lab of Clinical Neurochemistry, Section of Neurology, University of Perugia, Perugia, Italy.
  • Pasquier FResources and Research Memory Center (MRRC) of Distalz, LicendUniversity of Lille, INSERM, CHU Lille, UMR1172, Lille, France.
  • Pastor PFundació Docència i Recerca MútuaTerrassa and Movement Disorders Unit, Department of Neurology, University Hospital MútuaTerrassa, Terrassa, Spain.
  • Peloso GInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
  • Pérez-Cordón AResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Pérez-Tur JCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Pericard PUS 41-UMS 2014-PLBS, bilille, Université de Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, Lille, France.
  • Peters OInstitute of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität Zu Berlin, and Berlin Institute of Health, Berlin, Germany.
  • Pijnenburg YALAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Pineda JAUnidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain.
  • Piñol-Ripoll GUnitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain.
  • Pisanu CDepartment of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
  • Polak TDepartment of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital, Wuerzburg, Germany.
  • Popp JCHUV, Old Age Psychiatry, Department of Psychiatry, Lausanne, Switzerland.
  • Posthuma DDepartment of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije University, Amsterdam, the Netherlands.
  • Priller JGerman Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.
  • Puerta RResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Quenez ODepartment of Genetics and CNR-MAJ, Normandie University, UNIROUEN, INSERM U1245, CHU Rouen, Rouen, France.
  • Quintela IGrupo de Medicina Xenómica, Centro Nacional de Genotipado (CEGEN-PRB3-ISCIII), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
  • Thomassen JQDepartment of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark.
  • Rábano ACIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Rainero ICentre for Neurodegenerative Disorders, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
  • Rajabli FThe John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.
  • Ramakers IDepartment of Psychiatry & Neuropsychologie, Maastricht University, Alzheimer Center Limburg, Maastricht, the Netherlands.
  • Real LMUnidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain.
  • Reinders MJTDelft Bioinformatics Lab, Delft University of Technology, Delft, the Netherlands.
  • Reitz CGertrude H. Sergievsky Center, Columbia University, New York, NY, USA.
  • Reyes-Dumeyer DDepartment of Neurology, Columbia University, New York, NY, USA.
  • Ridge PBioinformatics, College of Life Sciences, Brigham Young University, Provo, UT, USA.
  • Riedel-Heller SInstitute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany.
  • Riederer PCenter of Mental Health, Clinic and Policlinic of Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Würzburg, Wuerzburg, Germany.
  • Roberto NResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Rodriguez-Rodriguez ECIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Rongve ADepartment of Research and Innovation, Helse Fonna, Haugesund Hospital, Haugesund, Norway.
  • Allende IRLaboratorio de Genética, Hospital Universitario Central de Asturias, Oviedo, Spain.
  • Rosende-Roca MResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Royo JLDepartamento de Especialidades Quirúrgicas, Bioquímicas e Inmunología, School of Medicine, University of Málaga, Málaga, Spain.
  • Rubino EDepartment of Neuroscience and Mental Health, AOU Città della Salute e della Scienza di Torino, Torino, Italy.
  • Rujescu DDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
  • Sáez MECAEBI, Centro Andaluz de Estudios Bioinformáticos, Sevilla, Spain.
  • Sakka PAthens Association of Alzheimer's Disease and Related Disorders, Athens, Greece.
  • Saltvedt IDepartment of Neurology and Clinical Neurophysiology, University Hospital of Trondheim, Trondheim, Norway.
  • Sanabria ÁResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Sánchez-Arjona MBUnidad de Demencias, Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.
  • Sanchez-Garcia FDepartment of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Las Palmas, Spain.
  • Juan PSCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Sánchez-Valle RNeurology Department-Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain.
  • Sando SBExperimental Neuro-psychobiology Laboratory, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy.
  • Sarnowski CHuman Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Satizabal CLDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • Scamosci MInstitute of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Scarmeas NTaub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.
  • Scarpini EFondazione IRCCS Ca'Granda, Ospedale Policlinico, Milan, Italy.
  • Scheltens PAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Scherbaum NLVR-Hospital Essen, Department of Psychiatry and Psychotherapy, Medical Faculty, University of Duisburg-Essen, Essen, Germany.
  • Scherer MDepartment of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
  • Schmid MGerman Center for Neurodegenerative Diseases (DZNE Bonn), Bonn, Germany.
  • Schneider ADepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
  • Schott JMDementia Research Centre, UCL Queen Square Institute of Neurology, London, UK.
  • Selbæk GInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
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  • Serrano MCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, CIBERDEM, Hospital Clínico San Carlos, Madrid, Spain.
  • Sha JDepartment of Biostatistics, Epidemiology, and Informatics, Penn Neurodegeneration Genomics Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Shadrin AANORMENT Centre, University of Oslo, Oslo, Norway.
  • Skrobot OTranslational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Slifer SThe John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.
  • Snijders GJLDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Soininen HInstitute of Clinical Medicine, Neurology, University of Eastern, Kuopio, Finland.
  • Solfrizzi VUniversity of Bari, "A. Moro", Bary, Italy.
  • Solomon AInstitute of Clinical Medicine, Neurology, University of Eastern, Kuopio, Finland.
  • Song YDepartment of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.
  • Sorbi SDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
  • Sotolongo-Grau OResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Spalletta GLaboratory of Neuropsychiatry, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy.
  • Spottke AGerman Center for Neurodegenerative Diseases (DZNE Bonn), Bonn, Germany.
  • Squassina ADepartment of Biomedical Sciences, Section of Neuroscience and Clinical Pharmacology, University of Cagliari, Cagliari, Italy.
  • Stordal EDepartment of Psychiatry, Namsos Hospital, Namsos, Norway.
  • Tartan JPResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Tárraga LResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Tesí NAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Thalamuthu ACentre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.
  • Thomas TFirst Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Tosto GTaub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.
  • Traykov LClinic of Neurology, UH 'Alexandrovska', Medical University - Sofia, Sofia, Bulgaria.
  • Tremolizzo LSchool of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy.
  • Tybjærg-Hansen ADepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Uitterlinden ADepartment of Internal Medicine and Biostatistics, Erasmus MC, Rotterdam, the Netherlands.
  • Ullgren ACenter for Alzheimer Research, Department NVS, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden.
  • Ulstein IDepartment of Geriatric Medicine, Oslo University Hospital, Oslo, Norway.
  • Valero SResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Valladares ODepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Broeckhoven CVComplex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.
  • Vance JDr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, FL, USA.
  • Vardarajan BNTaub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.
  • van der Lugt ADepartment of Neurology, ErasmusMC, Rotterdam, the Netherlands.
  • Dongen JVComplex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.
  • van Rooij JDepartment of Neurology, Erasmus MC, Rotterdam, the Netherlands.
  • van Swieten JDepartment of Neurology, Erasmus MC, Rotterdam, the Netherlands.
  • Vandenberghe RLaboratory for Cognitive Neurology, Department of Neurosciences, University of Leuven, Leuven, Belgium.
  • Verhey FDepartment of Psychiatry & Neuropsychologie, Maastricht University, Alzheimer Center Limburg, Maastricht, the Netherlands.
  • Vidal JSEA 4468, Université de Paris, APHP, Hôpital Broca, Paris, France.
  • Vogelgsang JDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.
  • Vyhnalek MMemory Clinic, Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Praha, Czechia.
  • Wagner MDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
  • Wallon DDepartment of Neurology and CNR-MAJ, F 76000, Normandy Center for Genomic and Personalized Medicine, Normandie University, UNIROUEN, INSERM U1245, CHU Rouen, Rouen, France.
  • Wang LSDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Wang RInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
  • Weinhold LInstitute of Medical Biometry, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany.
  • Wiltfang JDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.
  • Windle GSchool of Health Sciences, Bangor University, Bangor, UK.
  • Woods BSchool of Health Sciences, Bangor University, Bangor, UK.
  • Yannakoulia MDepartment of Nutrition and Diatetics, Harokopio University, Athens, Greece.
  • Zare HGlenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, USA.
  • Zhao YDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Zhang XDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.
  • Zhu CDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.
  • Zulaica MCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Farrer LAInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
  • Psaty BMFramingham Heart Study, Framingham, MA, USA.
  • Ghanbari MDepartment of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.
  • Raj TRonald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Sachdev PCentre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.
  • Mather KCentre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.
  • Jessen FDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
  • Ikram MADepartment of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.
  • de Mendonça AFaculty of Medicine, University of Lisbon, Lisbon, Portugal.
  • Hort JIntramural Research Program/National Institute on Aging/National Institutes of Health, Bethesda, MD, USA.
  • Tsolaki MFirst Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Pericak-Vance MAAI Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
  • Amouyel PUniversité de Lille, INSERM, CHU Lille, Institut Pasteur Lille, U1167-RID-AGE, Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.
  • Williams JMRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.
  • Frikke-Schmidt RDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Clarimon JCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
  • Deleuze JFCEA, Centre National de Recherche en Génomique Humaine, Université Paris-Saclay, Evry, France.
  • Rossi GFondazione IRCCS, Istituto Neurologico Carlo Besta, Milan, Italy.
  • Seshadri SDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • Andreassen OANORMENT Centre, University of Oslo, Oslo, Norway.
  • Ingelsson MDepartment of Public Health and Carins Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.
  • Hiltunen MBrain Institute, Federal University of Rio Grande do Norte, Natal, Brazil.
  • Sleegers KComplex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.
  • Schellenberg GDDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • van Duijn CMDepartment of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.
  • Sims RMRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.
  • van der Flier WMAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.
  • Ruiz AResearch Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
  • Ramirez ADepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
  • Lambert JCUniversité de Lille, INSERM, CHU Lille, Institut Pasteur Lille, U1167-RID-AGE, Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France. Jean-Charles.Lambert@pasteur-lille.fr.
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Eva Brown

Rigor 2/5Novelty 4/5Impact 3/5Reprod. 3/5

Replication is unclear to me.

0

Sam Sato

Rigor 5/5Novelty 3/5Impact 4/5Reprod. 4/5

Interesting idea, small sample.