Nat Biotechnol · 2013
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
Fu Y, Foden JA, Khayter C, Maeder ML, Reyon D, Joung JK, Sander JD.
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- Fu Y — 1] Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [2] Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [3] Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [4] Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.
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