Nat Neurosci · 2021

Reactive astrocyte nomenclature, definitions, and future directions

Escartin C, Galea E, Lakatos A, O'Callaghan JP, Petzold GC, Serrano-Pozo A, Steinhäuser C, Volterra A, Carmignoto G, Agarwal A, Allen NJ, Araque A, Barbeito L, Barzilai A, Bergles DE, Bonvento G, Butt AM, Chen WT, Cohen-Salmon M, Cunningham C, Deneen B, De Strooper B, Díaz-Castro B, Farina C, Freeman M, Gallo V, Goldman JE, Goldman SA, Götz M, Gutiérrez A, Haydon PG, Heiland DH, Hol EM, Holt MG, Iino M, Kastanenka KV, Kettenmann H, Khakh BS, Koizumi S, Lee CJ, Liddelow SA, MacVicar BA, Magistretti P, Messing A, Mishra A, Molofsky AV, Murai KK, Norris CM, Okada S, Oliet SHR, Oliveira JF, Panatier A, Parpura V, Pekna M, Pekny M, Pellerin L, Perea G, Pérez-Nievas BG, Pfrieger FW, Poskanzer KE, Quintana FJ, Ransohoff RM, Riquelme-Perez M, Robel S, Rose CR, Rothstein JD, Rouach N, Rowitch DH, Semyanov A, Sirko S, Sontheimer H, Swanson RA, Vitorica J, Wanner IB, Wood LB, Wu J, Zheng B, Zimmer ER, Zorec R, Sofroniew MV, Verkhratsky A.

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Escartin C — Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France. carole.escartin@cea.fr.
Galea E — Institut de Neurociències and Departament de Bioquímica i Biologia Molecular, Unitat de Bioquímica de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain. Elena.Galea@uab.es.
Lakatos A — John van Geest Centre for Brain Repair and Division of Stem Cell Neurobiology, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
O'Callaghan JP — Health Effects Laboratory Division, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA.
Petzold GC — German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Serrano-Pozo A — Alzheimer Research Unit, Department of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Steinhäuser C — Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, Bonn, Germany.
Volterra A — Department of Fundamental Neuroscience, University of Lausanne, Lausanne, Switzerland.
Carmignoto G — Neuroscience Institute, Italian National Research Council (CNR), Padua, Italy.
Agarwal A — The Chica and Heinz Schaller Research Group, Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany.
Allen NJ — Salk Institute for Biological Studies, Molecular Neurobiology Laboratory, La Jolla, California, USA.
Araque A — Department of Neuroscience, University of Minnesota, Minneapolis, Minnesota, USA.
Barbeito L — Institut Pasteur de Montevideo, Montevideo, Uruguay.
Barzilai A — Department of Neurobiology, George S. Wise, Faculty of Life Sciences and Sagol School of Neuroscience, Tel Aviv University, Ramat Aviv Tel Aviv, Israel.
Bergles DE — The Solomon H. Snyder Department of Neuroscience, Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Bonvento G — Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Butt AM — School of Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth, UK.
Chen WT — Center for Brain and Disease Research, VIB and University of Leuven, Leuven, Belgium.
Cohen-Salmon M — 'Physiology and Physiopathology of the Gliovascular Unit' Research Group, Center for Interdisciplinary Research in Biology (CIRB), College de France, Unité Mixte de Recherche 7241 CNRS, Unité1050 INSERM, PSL Research University, Paris, France.
Cunningham C — Trinity Biomedical Sciences Institute & Trinity College Institute of Neuroscience, School of Biochemistry & Immunology, Trinity College Dublin, Dublin, Republic of Ireland.
Deneen B — Center for Cell and Gene Therapy, Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA.
De Strooper B — Center for Brain and Disease Research, VIB and University of Leuven, Leuven, Belgium.
Díaz-Castro B — UK Dementia Research Institute at the University of Edinburgh, Centre for Discovery Brain Sciences, Edinburgh, UK.
Farina C — Institute of Experimental Neurology (INSpe) and Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy.
Freeman M — Vollum Institute, OHSU, Portland, Oregon, USA.
Gallo V — Center for Neuroscience Research, Children's National Research Institute, Children's National Hospital, Washington DC, USA.
Goldman JE — Department of Pathology & Cell Biology, Columbia University, New York, New York, USA.
Goldman SA — University of Rochester Medical Center, Rochester, New York, USA.
Götz M — Physiological Genomics, Biomedical Center, Ludwig-Maximilians-Universitaet & Institute of Stem Cell Research, Helmholtz Center Munich, Munich, Germany.
Gutiérrez A — Dpto. Biología Celular, Genética y Fisiología, Instituto de Investigación Biomédica de Málaga-IBIMA, Facultad de Ciencias, Universidad de Málaga, Málaga, Spain.
Haydon PG — Department of Neuroscience, Tufts University School of Medicine, Boston, Massachusetts, USA.
Heiland DH — Microenvironment and Immunology Research Laboratory, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Hol EM — Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.
Holt MG — Laboratory of Glia Biology, VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium.
Iino M — Division of Cellular and Molecular Pharmacology, Nihon University School of Medicine, Tokyo, Japan.
Kastanenka KV — Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.
Kettenmann H — Cellular Neurosciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
Khakh BS — Department of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Koizumi S — Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Lee CJ — Center for Cognition and Sociality, Institute for Basic Science 55, Expo-ro, Yuseong-gu, Daejeon, Korea.
Liddelow SA — Neuroscience Institute, Department of Neuroscience and Physiology, Department of Ophthalmology, NYU School of Medicine, New York, USA.
MacVicar BA — Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.
Magistretti P — Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
Messing A — Waisman Center and School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Mishra A — Department of Neurology Jungers Center for Neurosciences Research and Knight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon, USA.
Molofsky AV — Departments of Psychiatry/Weill Institute for Neuroscience University of California, San Francisco, California, USA.
Murai KK — Centre for Research in Neuroscience, Department of Neurology & Neurosurgery, Brain Repair and Integrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Norris CM — Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Okada S — Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Oliet SHR — Université de Bordeaux, Inserm, Neurocentre Magendie, U1215, Bordeaux, France.
Oliveira JF — Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Panatier A — Université de Bordeaux, Inserm, Neurocentre Magendie, U1215, Bordeaux, France.
Parpura V — Department of Neurobiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Pekna M — Laboratory of Regenerative Neuroimmunology, Center for Brain Repair, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Pekny M — Laboratory of Astrocyte Biology and CNS Regeneration, Center for Brain Repair, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Pellerin L — INSERM U1082, Université de Poitiers, Poitiers, France.
Perea G — Department of Functional and Systems Neurobiology, Cajal Institute, CSIC, Madrid, Spain.
Pérez-Nievas BG — Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Pfrieger FW — Centre National de la Recherche Scientifique, Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives, Strasbourg, France.
Poskanzer KE — Department of Biochemistry & Biophysics, Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, California, USA.
Quintana FJ — Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School. Associate Member, The Broad Institute, Boston, Massachusetts, USA.
Ransohoff RM — Third Rock Ventures, Boston, Massachusetts, USA.
Riquelme-Perez M — Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Robel S — Fralin Biomedical Research Institute at Virginia Tech Carilion, School of Neuroscience Virginia Tech, Riverside Circle, Roanoke, Virginia, USA.
Rose CR — Institute of Neurobiology, Heinrich Heine University, Düsseldorf, Germany.
Rothstein JD — Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Rouach N — Neuroglial Interactions in Cerebral Physiology and Pathologies, Center for Interdisciplinary Research in Biology, Collège de France, CNRS UMR 7241, INSERM U1050, Labex Memolife, PSL Research University Paris, Paris, France.
Rowitch DH — Wellcome Trust-MRC Cambridge Stem Cell Institute, Cambridge Biomedical Campus, Cambridge, UK.
Semyanov A — Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.
Sirko S — Physiological Genomics, Biomedical Center, LMU Munich, Munich, Germany.
Sontheimer H — Virginia Tech School of Neuroscience and Center for Glial Biology in Health, Disease and Cancer, Virginia Tech at the Fralin Biomedical Research Institute, Roanoke, Virginia, USA.
Swanson RA — Dept. of Neurology, University of California San Francisco and San Francisco Veterans Affairs Health Care System, San Francisco, California, USA.
Vitorica J — Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Wanner IB — Semel Institute for Neuroscience & Human Behavior, IDDRC, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.
Wood LB — George W. Woodruff School of Mechanical Engineering, Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory, and Parker H. Petit Institute for Bioengineering & Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA.
Wu J — The Vivian L. Smith Department of Neurosurgery, Center for Stem Cell and Regenerative Medicine, MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, McGovern Medical School, UTHealth, University of Texas Health Science Center at Houston, Houston, TX, USA.
Zheng B — Department of Neurosciences, UC San Diego School of Medicine, La Jolla; VA San Diego Research Service, San Diego, CA, USA.
Zimmer ER — Department of Pharmacology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Zorec R — Laboratory of Neuroendocrinology, Molecular Cell Physiology, Institute of Pathophysiology, University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia.
Sofroniew MV — Department of Neurobiology, David Geffen School of Medicine, University of California, Los Angeles, California, USA. sofroniew@mednet.ucla.edu.
Verkhratsky A — Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK. alexej.verkhratsky@manchester.ac.uk.