Nat Genet · 2009

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, Heun R, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Holmans PA, O'Donovan M, Owen MJ, Williams J.

Show affiliations
  • Harold DMedical Research Council Centre for Neuropsychiatric Genetics and Genomics, Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Cardiff, UK.
40 read4 want to readRigor 3.1Novelty 2.7Impact 2.6Reprod. 2.5

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0

Jonas Silva

Rigor 4/5Novelty 3/5Impact 4/5Reprod. 3/5

Nice but incremental.

0

Ken Nguyen

Rigor 4/5Novelty 3/5Impact 1/5Reprod. 2/5

Replication is unclear to me.

0

Hugo Smith

Rigor 3/5Novelty 5/5Impact 3/5Reprod. 4/5

Replication is unclear to me.

0

Noor Brown

Rigor 5/5Novelty 2/5Impact 1/5Reprod. 2/5

Important contribution to the field.

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Mei Brown

Rigor 4/5Novelty 3/5Impact 2/5Reprod. 1/5

Great figures and clear story.

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Sara Khan

Rigor 2/5Novelty 1/5Impact 4/5Reprod. 3/5

Interesting idea, small sample.

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Omar Smith

Rigor 4/5Novelty 1/5Impact 1/5Reprod. 4/5

Important contribution to the field.