Nat Genet · 2009

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, Heun R, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Holmans PA, O'Donovan M, Owen MJ, Williams J.

Show affiliations
  • Harold D — Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Cardiff, UK.
40 read4 want to readRigor 3.1Novelty 2.7Impact 2.6Reprod. 2.5

Most-cited papers citing this

  • Alzheimers Dement · 2025 · cited by 45
  • Neuron · 2025 · cited by 39
  • Acta Pharm Sin B · 2025 · cited by 29
  • Mol Ther Nucleic Acids · 2025 · cited by 22
  • CNS Neurosci Ther · 2025 · cited by 20

Log in to like, log, and share thoughts on this paper.

Discussion

Share your thoughts above to start a thread. Constructive feedback only — reply to and like others’ posts.

0

Jonas Silva

Rigor 4/5Novelty 3/5Impact 4/5Reprod. 3/5

Nice but incremental.

0

Ken Nguyen

Rigor 4/5Novelty 3/5Impact 1/5Reprod. 2/5

Replication is unclear to me.

0

Hugo Smith

Rigor 3/5Novelty 5/5Impact 3/5Reprod. 4/5

Replication is unclear to me.

0

Noor Brown

Rigor 5/5Novelty 2/5Impact 1/5Reprod. 2/5

Important contribution to the field.

0

Mei Brown

Rigor 4/5Novelty 3/5Impact 2/5Reprod. 1/5

Great figures and clear story.

0

Sara Khan

Rigor 2/5Novelty 1/5Impact 4/5Reprod. 3/5

Interesting idea, small sample.

0

Omar Smith

Rigor 4/5Novelty 1/5Impact 1/5Reprod. 4/5

Important contribution to the field.