N Engl J Med · 2014

Chimeric antigen receptor T cells for sustained remissions in leukemia

Maude SL, Frey N, Shaw PA, Aplenc R, Barrett DM, Bunin NJ, Chew A, Gonzalez VE, Zheng Z, Lacey SF, Mahnke YD, Melenhorst JJ, Rheingold SR, Shen A, Teachey DT, Levine BL, June CH, Porter DL, Grupp SA.

Show affiliations
  • Maude SLFrom the Division of Oncology, Children's Hospital of Philadelphia (S.L.M., R.A., D.M.B., N.J.B., S.R.R., D.T.T., S.A.G.), the Departments of Pediatrics (S.L.M., R.A., D.M.B., N.J.B., S.R.R., D.T.T., S.A.G.), Biostatistics and Epidemiology (P.A.S., R.A.), and Pathology and Laboratory Medicine (J.J.M., B.L.L., C.H.J., S.A.G.), the Division of Hematology-Oncology (N.F., D.L.P.), and Abramson Cancer Center (N.F., A.C., V.E.G., Z.Z., S.F.L., Y.D.M., J.J.M., B.L.L., C.H.J., D.L.P., S.A.G.), Perelman School of Medicine, University of Pennsylvania - all in Philadelphia; and Novartis Pharmaceuticals, East Hanover, NJ (A.S.).
25 read3 want to readRigor 2.9Novelty 3.3Impact 2.8Reprod. 3.4

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0

Sara Sato

Rigor 4/5Novelty 5/5Impact 3/5Reprod. 3/5

Interesting idea, small sample.

0

Sam Brown

Rigor 2/5Novelty 4/5Impact 5/5Reprod. 4/5

Replication is unclear to me.

0

Sara Cohen

Rigor 3/5Novelty 5/5Impact 4/5Reprod. 5/5

Replication is unclear to me.

0

Omar Kim

Rigor 5/5Novelty 5/5Impact 2/5Reprod. 2/5

Great figures and clear story.

0

Jonas Silva

Rigor 2/5Novelty 3/5Impact 3/5Reprod. 5/5

Solid methods, convincing results.

0

Alex Cohen

Rigor 1/5Novelty 3/5Impact 2/5Reprod. 5/5

Solid methods, convincing results.