Cell · 2013
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
Ran FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y, Zhang F.
Show affiliations
- Ran FA — Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
58 read10 want to readRigor 2.6Novelty 3.3Impact 2.8Reprod. 3.1
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0
Jonas Sato
Rigor 1/5Novelty 3/5Impact 2/5Reprod. 2/5
0
Maya Smith
Rigor 1/5Novelty 4/5Impact 4/5Reprod. 1/5
Interesting idea, small sample.
0
Eva Park
Rigor 3/5Novelty 1/5Impact 2/5Reprod. 2/5
Important contribution to the field.
0
Noor Rossi
Rigor 5/5Novelty 4/5Impact 3/5Reprod. 5/5
Replication is unclear to me.
0
Ines Rossi
Rigor 5/5Novelty 4/5Impact 4/5Reprod. 2/5
0
Tom Mueller
Rigor 1/5Novelty 2/5Impact 5/5Reprod. 2/5
Important contribution to the field.
0
Eva Wang
Rigor 1/5Novelty 1/5Impact 2/5Reprod. 3/5
Important contribution to the field.
0
Maya Lee
Rigor 3/5Novelty 5/5Impact 5/5Reprod. 2/5
Great figures and clear story.
0
Tariq Lee
Rigor 1/5Novelty 1/5Impact 1/5Reprod. 4/5
Replication is unclear to me.
0
Sam Sato
Rigor 4/5Novelty 4/5Impact 4/5Reprod. 5/5
Replication is unclear to me.
0
Pablo Silva
Rigor 2/5Novelty 3/5Impact 4/5Reprod. 5/5
Interesting idea, small sample.
0
Jonas Nguyen
Rigor 5/5Novelty 1/5Impact 1/5Reprod. 5/5
Interesting idea, small sample.
0
Tom Park
Rigor 4/5Novelty 1/5Impact 4/5Reprod. 1/5
Solid methods, convincing results.
0
Lena Nguyen
Rigor 5/5Novelty 5/5Impact 4/5Reprod. 4/5
Great figures and clear story.
0
Alex Park
Rigor 1/5Novelty 4/5Impact 4/5Reprod. 3/5
Replication is unclear to me.
0
Alex Rossi
Rigor 1/5Novelty 2/5Impact 3/5Reprod. 5/5
Great figures and clear story.
0
Eva Mueller
Rigor 4/5Novelty 5/5Impact 1/5Reprod. 2/5
Solid methods, convincing results.
0
Hugo Garcia
Rigor 3/5Novelty 1/5Impact 3/5Reprod. 3/5
Important contribution to the field.
0
Hugo Smith
Rigor 3/5Novelty 4/5Impact 1/5Reprod. 3/5
Replication is unclear to me.
0
Pablo Smith
Rigor 1/5Novelty 3/5Impact 5/5Reprod. 1/5
Important contribution to the field.