Cancer Cell · 2015

Immune checkpoint blockade: a common denominator approach to cancer therapy

Topalian SL, Drake CG, Pardoll DM.

Show affiliations
  • Topalian SLDepartment of Surgery, Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address: stopali1@jhmi.edu.
  • Drake CGThe Brady Urological Institute, Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Pardoll DMDepartment of Oncology, Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
36 read4 want to readRigor 2.8Novelty 2.9Impact 2.8Reprod. 3.0

Most-cited papers citing this

  • MedComm (2020) · 2025 · cited by 4
  • J Invest Dermatol · 2026 · cited by 4
  • Drug Deliv · 2025 · cited by 3
  • Sci Rep · 2025 · cited by 3
  • Cancer Res · 2025 · cited by 2

Log in to like, log, and share thoughts on this paper.

Discussion

Share your thoughts above to start a thread. Constructive feedback only — reply to and like others’ posts.

0

Pablo Brown

Rigor 2/5Novelty 3/5Impact 2/5Reprod. 4/5

Important contribution to the field.

0

Sara Khan

Rigor 2/5Novelty 3/5Impact 4/5Reprod. 1/5

Solid methods, convincing results.

0

Noor Rossi

Rigor 2/5Novelty 1/5Impact 4/5Reprod. 3/5

Great figures and clear story.

0

Hugo Mueller

Rigor 1/5Novelty 4/5Impact 4/5Reprod. 3/5

Solid methods, convincing results.

0

Liam Kim

Rigor 5/5Novelty 3/5Impact 2/5Reprod. 2/5

Great figures and clear story.

0

Mei Garcia

Rigor 1/5Novelty 5/5Impact 2/5Reprod. 5/5

Solid methods, convincing results.

0

Pablo Lee

Rigor 5/5Novelty 4/5Impact 1/5Reprod. 3/5

Important contribution to the field.

0

Jonas Lee

Rigor 1/5Novelty 1/5Impact 2/5Reprod. 2/5

Replication is unclear to me.

0

Eva Silva

Rigor 5/5Novelty 5/5Impact 1/5Reprod. 5/5

Great figures and clear story.

0

Hugo Patel

Rigor 3/5Novelty 2/5Impact 2/5Reprod. 3/5

Replication is unclear to me.

0

Tariq Patel

Rigor 4/5Novelty 4/5Impact 2/5Reprod. 2/5

Great figures and clear story.