Sara Brown

Liked papers (25)

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease

Sampson TR, Debelius JW, Thron T, Janssen S, Shastri GG, Ilhan ZE, Challis C, Schretter CE, Rocha S, Gradinaru V, Chesselet MF, Keshavarzian A, Shannon KM, Krajmalnik-Brown R, Wittung-Stafshede P, Knight R, Mazmanian SK.

Cell · 2016

Integrative analysis of 111 reference human epigenomes

Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coarfa C, Harris RA, Shoresh N, Epstein CB, Gjoneska E, Leung D, Xie W, Hawkins RD, Lister R, Hong C, Gascard P, Mungall AJ, Moore R, Chuah E, Tam A, Canfield TK, Hansen RS, Kaul R, Sabo PJ, Bansal MS, Carles A, Dixon JR, Farh KH, Feizi S, Karlic R, Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA, Stevens M, Thurman RE, Wu J, Zhang B, Zhou X, Beaudet AE, Boyer LA, De Jager PL, Farnham PJ, Fisher SJ, Haussler D, Jones SJ, Li W, Marra MA, McManus MT, Sunyaev S, Thomson JA, Tlsty TD, Tsai LH, Wang W, Waterland RA, Zhang MQ, Chadwick LH, Bernstein BE, Costello JF, Ecker JR, Hirst M, Meissner A, Milosavljevic A, Ren B, Stamatoyannopoulos JA, Wang T, Kellis M.

Nature · 2015

PD-1 and its ligands in tolerance and immunity

Keir ME, Butte MJ, Freeman GJ, Sharpe AH.

Annu Rev Immunol · 2008

The Genotype-Tissue Expression (GTEx) project

GTEx Consortium.

Nat Genet · 2013

Innate and adaptive immune cells in the tumor microenvironment

Gajewski TF, Schreiber H, Fu YX.

Nat Immunol · 2013

CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes

Parks DH, Imelfort M, Skennerton CT, Hugenholtz P, Tyson GW.

Genome Res · 2015

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

Doudna JA, Charpentier E.

Science · 2014

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Lazarou M, Sliter DA, Kane LA, Sarraf SA, Wang C, Burman JL, Sideris DP, Fogel AI, Youle RJ.

Nature · 2015

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, Sun Y, Jacobsen A, Sinha R, Larsson E, Cerami E, Sander C, Schultz N.

Sci Signal · 2013

The future of immune checkpoint therapy

Sharma P, Allison JP.

Science · 2015

The blockade of immune checkpoints in cancer immunotherapy

Pardoll DM.

Nat Rev Cancer · 2012

MicroRNAs: target recognition and regulatory functions

Bartel DP.

Cell · 2009

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

Mali P, Aach J, Stranges PB, Esvelt KM, Moosburner M, Kosuri S, Yang L, Church GM.

Nat Biotechnol · 2013

Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads

Wick RR, Judd LM, Gorrie CL, Holt KE.

PLoS Comput Biol · 2017

Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions

Lupiáñez DG, Kraft K, Heinrich V, Krawitz P, Brancati F, Klopocki E, Horn D, Kayserili H, Opitz JM, Laxova R, Santos-Simarro F, Gilbert-Dussardier B, Wittler L, Borschiwer M, Haas SA, Osterwalder M, Franke M, Timmermann B, Hecht J, Spielmann M, Visel A, Mundlos S.

Cell · 2015

Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry

Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K.

Acta Neuropathol · 2006

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Love MI, Huber W, Anders S.

Genome Biol · 2014

Full-length transcriptome assembly from RNA-Seq data without a reference genome

Grabherr MG, Haas BJ, Yassour M, Levin JZ, Thompson DA, Amit I, Adiconis X, Fan L, Raychowdhury R, Zeng Q, Chen Z, Mauceli E, Hacohen N, Gnirke A, Rhind N, di Palma F, Birren BW, Nusbaum C, Lindblad-Toh K, Friedman N, Regev A.

Nat Biotechnol · 2011

Human MicroRNA targets

John B, Enright AJ, Aravin A, Tuschl T, Sander C, Marks DS.

PLoS Biol · 2004

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J.

Nature · 2000

Multi-omics approaches to disease

Hasin Y, Seldin M, Lusis A.

Genome Biol · 2017

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

Lambert MP, Barlow AK, Chromy BA, Edwards C, Freed R, Liosatos M, Morgan TE, Rozovsky I, Trommer B, Viola KL, Wals P, Zhang C, Finch CE, Krafft GA, Klein WL.

Proc Natl Acad Sci U S A · 1998

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS.

Cell · 2014

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Komor AC, Kim YB, Packer MS, Zuris JA, Liu DR.

Nature · 2016

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

Wallace DC.

Annu Rev Genet · 2005