Ken Lee

Liked papers (20)

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

Sreedharan J, Blair IP, Tripathi VB, Hu X, Vance C, Rogelj B, Ackerley S, Durnall JC, Williams KL, Buratti E, Baralle F, de Belleroche J, Mitchell JD, Leigh PN, Al-Chalabi A, Miller CC, Nicholson G, Shaw CE.

Science · 2008

The neuropathological diagnosis of Alzheimer's disease

DeTure MA, Dickson DW.

Mol Neurodegener · 2019

Elements of cancer immunity and the cancer-immune set point

Chen DS, Mellman I.

Nature · 2017

mTOR at the nexus of nutrition, growth, ageing and disease

Liu GY, Sabatini DM.

Nat Rev Mol Cell Biol · 2020

STAR: ultrafast universal RNA-seq aligner

Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, Batut P, Chaisson M, Gingeras TR.

Bioinformatics · 2013

Wnt signaling in cancer

Zhan T, Rindtorff N, Boutros M.

Oncogene · 2017

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

Long JM, Holtzman DM.

Cell · 2019

Lipid nanoparticles for mRNA delivery

Hou X, Zaks T, Langer R, Dong Y.

Nat Rev Mater · 2021

Expanded encyclopaedias of DNA elements in the human and mouse genomes

ENCODE Project Consortium, Moore JE, Purcaro MJ, Pratt HE, Epstein CB, Shoresh N, Adrian J, Kawli T, Davis CA, Dobin A, Kaul R, Halow J, Van Nostrand EL, Freese P, Gorkin DU, Shen Y, He Y, Mackiewicz M, Pauli-Behn F, Williams BA, Mortazavi A, Keller CA, Zhang XO, Elhajjajy SI, Huey J, Dickel DE, Snetkova V, Wei X, Wang X, Rivera-Mulia JC, Rozowsky J, Zhang J, Chhetri SB, Zhang J, Victorsen A, White KP, Visel A, Yeo GW, Burge CB, Lécuyer E, Gilbert DM, Dekker J, Rinn J, Mendenhall EM, Ecker JR, Kellis M, Klein RJ, Noble WS, Kundaje A, Guigó R, Farnham PJ, Cherry JM, Myers RM, Ren B, Graveley BR, Gerstein MB, Pennacchio LA, Snyder MP, Bernstein BE, Wold B, Hardison RC, Gingeras TR, Stamatoyannopoulos JA, Weng Z.

Nature · 2020

Innate and adaptive immune cells in the tumor microenvironment

Gajewski TF, Schreiber H, Fu YX.

Nat Immunol · 2013

Integrated analysis of multimodal single-cell data

Hao Y, Hao S, Andersen-Nissen E, Mauck WM, Zheng S, Butler A, Lee MJ, Wilk AJ, Darby C, Zager M, Hoffman P, Stoeckius M, Papalexi E, Mimitou EP, Jain J, Srivastava A, Stuart T, Fleming LM, Yeung B, Rogers AJ, McElrath JM, Blish CA, Gottardo R, Smibert P, Satija R.

Cell · 2021

Role of the microbiota in immunity and inflammation

Belkaid Y, Hand TW.

Cell · 2014

Human MicroRNA targets

John B, Enright AJ, Aravin A, Tuschl T, Sander C, Marks DS.

PLoS Biol · 2004

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

Tsai SQ, Zheng Z, Nguyen NT, Liebers M, Topkar VV, Thapar V, Wyvekens N, Khayter C, Iafrate AJ, Le LP, Aryee MJ, Joung JK.

Nat Biotechnol · 2015

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

Mali P, Aach J, Stranges PB, Esvelt KM, Moosburner M, Kosuri S, Yang L, Church GM.

Nat Biotechnol · 2013

Metagenomic biomarker discovery and explanation

Segata N, Izard J, Waldron L, Gevers D, Miropolsky L, Garrett WS, Huttenhower C.

Genome Biol · 2011

Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

Schreiber RD, Old LJ, Smyth MJ.

Science · 2011

TREM2 variants in Alzheimer's disease

Guerreiro R, Wojtas A, Bras J, Carrasquillo M, Rogaeva E, Majounie E, Cruchaga C, Sassi C, Kauwe JS, Younkin S, Hazrati L, Collinge J, Pocock J, Lashley T, Williams J, Lambert JC, Amouyel P, Goate A, Rademakers R, Morgan K, Powell J, St George-Hyslop P, Singleton A, Hardy J, Alzheimer Genetic Analysis Group.

N Engl J Med · 2013

A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β

Iliff JJ, Wang M, Liao Y, Plogg BA, Peng W, Gundersen GA, Benveniste H, Vates GE, Deane R, Goldman SA, Nagelhus EA, Nedergaard M.

Sci Transl Med · 2012

The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions

Oughtred R, Rust J, Chang C, Breitkreutz BJ, Stark C, Willems A, Boucher L, Leung G, Kolas N, Zhang F, Dolma S, Coulombe-Huntington J, Chatr-Aryamontri A, Dolinski K, Tyers M.

Protein Sci · 2021