Sam Mueller

Liked papers (13)

Drugging the undruggable RAS: Mission possible?

Cox AD, Fesik SW, Kimmelman AC, Luo J, Der CJ.

Nat Rev Drug Discov · 2014

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Hardy J, Selkoe DJ.

Science · 2002

Alzheimer's disease: genes, proteins, and therapy

Selkoe DJ.

Physiol Rev · 2001

Neuroinflammation in Alzheimer's disease

Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, Yamanaka K, Koistinaho J, Latz E, Halle A, Petzold GC, Town T, Morgan D, Shinohara ML, Perry VH, Holmes C, Bazan NG, Brooks DJ, Hunot S, Joseph B, Deigendesch N, Garaschuk O, Boddeke E, Dinarello CA, Breitner JC, Cole GM, Golenbock DT, Kummer MP.

Lancet Neurol · 2015

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade

Charoentong P, Finotello F, Angelova M, Mayer C, Efremova M, Rieder D, Hackl H, Trajanoski Z.

Cell Rep · 2017

Structure, function and diversity of the healthy human microbiome

Human Microbiome Project Consortium.

Nature · 2012

RNA-programmed genome editing in human cells

Jinek M, East A, Cheng A, Lin S, Ma E, Doudna J.

Elife · 2013

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

Zlokovic BV.

Nat Rev Neurosci · 2011

Neuropathological stageing of Alzheimer-related changes

Braak H, Braak E.

Acta Neuropathol · 1991

Diversity of the human intestinal microbial flora

Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, Gill SR, Nelson KE, Relman DA.

Science · 2005

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

Vassar R, Bennett BD, Babu-Khan S, Kahn S, Mendiaz EA, Denis P, Teplow DB, Ross S, Amarante P, Loeloff R, Luo Y, Fisher S, Fuller J, Edenson S, Lile J, Jarosinski MA, Biere AL, Curran E, Burgess T, Louis JC, Collins F, Treanor J, Rogers G, Citron M.

Science · 1999

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

Hangauer MJ, Viswanathan VS, Ryan MJ, Bole D, Eaton JK, Matov A, Galeas J, Dhruv HD, Berens ME, Schreiber SL, McCormick F, McManus MT.

Nature · 2017

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

Livingston G, Huntley J, Sommerlad A, Ames D, Ballard C, Banerjee S, Brayne C, Burns A, Cohen-Mansfield J, Cooper C, Costafreda SG, Dias A, Fox N, Gitlin LN, Howard R, Kales HC, Kivimäki M, Larson EB, Ogunniyi A, Orgeta V, Ritchie K, Rockwood K, Sampson EL, Samus Q, Schneider LS, Selbæk G, Teri L, Mukadam N.

Lancet · 2020