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Nature · 2012

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT.

Nature · 2013

mTOR at the nexus of nutrition, growth, ageing and disease

Liu GY, Sabatini DM.

Nat Rev Mol Cell Biol · 2020

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD.

Proc Natl Acad Sci U S A · 1993

Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice

Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G.

Science · 1996

The Human Cell Atlas

Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe'er D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N, Human Cell Atlas Meeting Participants

eLife · 2017

Inferring tumour purity and stromal and immune cell admixture from expression data

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Nat Commun · 2013

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Neuhaus J, van Swieten JC, Seelaar H, Dopper EG, Onyike CU, Hillis AE, Josephs KA, Boeve BF, Kertesz A, Seeley WW, Rankin KP, Johnson JK, Gorno-Tempini ML, Rosen H, Prioleau-Latham CE, Lee A, Kipps CM, Lillo P, Piguet O, Rohrer JD, Rossor MN, Warren JD, Fox NC, Galasko D, Salmon DP, Black SE, Mesulam M, Weintraub S, Dickerson BC, Diehl-Schmid J, Pasquier F, Deramecourt V, Lebert F, Pijnenburg Y, Chow TW, Manes F, Grafman J, Cappa SF, Freedman M, Grossman M, Miller BL.

Brain · 2011

Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection

Eyquem J, Mansilla-Soto J, Giavridis T, van der Stegen SJ, Hamieh M, Cunanan KM, Odak A, Gönen M, Sadelain M.

Nature · 2017

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients

Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA.

Science · 2018

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM.

Neuron · 2003

Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

Langille MG, Zaneveld J, Caporaso JG, McDonald D, Knights D, Reyes JA, Clemente JC, Burkepile DE, Vega Thurber RL, Knight R, Beiko RG, Huttenhower C.

Nat Biotechnol · 2013

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Alvarez-Erviti L, Seow Y, Yin H, Betts C, Lakhal S, Wood MJ.

Nat Biotechnol · 2011

A scaling normalization method for differential expression analysis of RNA-seq data

Robinson MD, Oshlack A.

Genome Biol · 2010

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

Edgar R, Domrachev M, Lash AE.

Nucleic Acids Res · 2002

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

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Cell · 2019

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

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Neuron · 2011

Liked papers (27)

Ferroptosis: mechanisms, biology and role in disease

Alzheimer's disease is a synaptic failure

Integrated genomic analyses of ovarian carcinoma

Spatial reconstruction of single-cell gene expression data

RNA-Seq: a revolutionary tool for transcriptomics

Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups