Liked papers (26)

Development and applications of CRISPR-Cas9 for genome engineering

Hsu PD, Lander ES, Zhang F.

Cell · 2014

A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping

Rao SS, Huntley MH, Durand NC, Stamenova EK, Bochkov ID, Robinson JT, Sanborn AL, Machol I, Omer AD, Lander ES, Aiden EL.

Cell · 2014

Microglia Function in the Central Nervous System During Health and Neurodegeneration

Colonna M, Butovsky O.

Annu Rev Immunol · 2017

The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR, Kawas CH, Klunk WE, Koroshetz WJ, Manly JJ, Mayeux R, Mohs RC, Morris JC, Rossor MN, Scheltens P, Carrillo MC, Thies B, Weintraub S, Phelps CH.

Alzheimers Dement · 2011

The amyloid hypothesis of Alzheimer's disease at 25 years

Selkoe DJ, Hardy J.

EMBO Mol Med · 2016

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

Tsai SQ, Zheng Z, Nguyen NT, Liebers M, Topkar VV, Thapar V, Wyvekens N, Khayter C, Iafrate AJ, Le LP, Aryee MJ, Joung JK.

Nat Biotechnol · 2015

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

Thorvaldsdóttir H, Robinson JT, Mesirov JP.

Brief Bioinform · 2013

Alzheimer's disease

Querfurth HW, LaFerla FM.

N Engl J Med · 2010

Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry

Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K.

Acta Neuropathol · 2006

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation

Oakley H, Cole SL, Logan S, Maus E, Shao P, Craft J, Guillozet-Bongaarts A, Ohno M, Disterhoft J, Van Eldik L, Berry R, Vassar R.

J Neurosci · 2006

IL-6 in inflammation, immunity, and disease

Tanaka T, Narazaki M, Kishimoto T.

Cold Spring Harb Perspect Biol · 2014

A scaling normalization method for differential expression analysis of RNA-seq data

Robinson MD, Oshlack A.

Genome Biol · 2010

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

Haass C, Selkoe DJ.

Nat Rev Mol Cell Biol · 2007

An updated evolutionary classification of CRISPR-Cas systems

Makarova KS, Wolf YI, Alkhnbashi OS, Costa F, Shah SA, Saunders SJ, Barrangou R, Brouns SJ, Charpentier E, Haft DH, Horvath P, Moineau S, Mojica FJ, Terns RM, Terns MP, White MF, Yakunin AF, Garrett RA, van der Oost J, Backofen R, Koonin EV.

Nat Rev Microbiol · 2015

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

Kim D, Paggi JM, Park C, Bennett C, Salzberg SL.

Nat Biotechnol · 2019

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ.

Nat Methods · 2013

The blockade of immune checkpoints in cancer immunotherapy

Pardoll DM.

Nat Rev Cancer · 2012

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

Fu Y, Foden JA, Khayter C, Maeder ML, Reyon D, Joung JK, Sander JD.

Nat Biotechnol · 2013

National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Thies B, Trojanowski JQ, Vinters HV, Montine TJ.

Alzheimers Dement · 2012

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE.

Science · 2014

An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management

Raghu G, Collard HR, Egan JJ, Martinez FJ, Behr J, Brown KK, Colby TV, Cordier JF, Flaherty KR, Lasky JA, Lynch DA, Ryu JH, Swigris JJ, Wells AU, Ancochea J, Bouros D, Carvalho C, Costabel U, Ebina M, Hansell DM, Johkoh T, Kim DS, King TE, Kondoh Y, Myers J, Müller NL, Nicholson AG, Richeldi L, Selman M, Dudden RF, Griss BS, Protzko SL, Schünemann HJ, ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis.

Am J Respir Crit Care Med · 2011