Pablo Lee

All read papers (39)

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

Chen EY, Tan CM, Kou Y, Duan Q, Wang Z, Meirelles GV, Clark NR, Ma'ayan A.

BMC Bioinformatics · 2013

4.0/5

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM.

Neuron · 2003

4.3/5

Easy quantitative assessment of genome editing by sequence trace decomposition

Brinkman EK, Chen T, Amendola M, van Steensel B.

Nucleic Acids Res · 2014

3.8/5

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation

Oakley H, Cole SL, Logan S, Maus E, Shao P, Craft J, Guillozet-Bongaarts A, Ohno M, Disterhoft J, Van Eldik L, Berry R, Vassar R.

J Neurosci · 2006

4.0/5

TIMER2.0 for analysis of tumor-infiltrating immune cells

Li T, Fu J, Zeng Z, Cohen D, Li J, Chen Q, Li B, Liu XS.

Nucleic Acids Res · 2020

3.5/5

IL-6 in inflammation, immunity, and disease

Tanaka T, Narazaki M, Kishimoto T.

Cold Spring Harb Perspect Biol · 2014

3.5/5

Comprehensive molecular portraits of human breast tumours

Cancer Genome Atlas Network.

Nature · 2012

2.8/5

STAR: ultrafast universal RNA-seq aligner

Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, Batut P, Chaisson M, Gingeras TR.

Bioinformatics · 2013

3.0/5

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

Sikorski RS, Hieter P.

Genetics · 1989

4.0/5

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

Jack CR, Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB, Holtzman DM, Jagust W, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, Rowe CC, Scheltens P, Siemers E, Snyder HM, Sperling R, Contributors.

Alzheimers Dement · 2018

2.3/5

Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy

Sharma P, Hu-Lieskovan S, Wargo JA, Ribas A.

Cell · 2017

2.0/5

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

Liu CC, Liu CC, Kanekiyo T, Xu H, Bu G.

Nat Rev Neurol · 2013

3.0/5

Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing

Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH, Swaminathan B.

J Clin Microbiol · 1995

3.8/5

Immune checkpoint blockade: a common denominator approach to cancer therapy

Topalian SL, Drake CG, Pardoll DM.

Cancer Cell · 2015

3.3/5

Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer

Borghaei H, Paz-Ares L, Horn L, Spigel DR, Steins M, Ready NE, Chow LQ, Vokes EE, Felip E, Holgado E, Barlesi F, Kohlhäufl M, Arrieta O, Burgio MA, Fayette J, Lena H, Poddubskaya E, Gerber DE, Gettinger SN, Rudin CM, Rizvi N, Crinò L, Blumenschein GR, Antonia SJ, Dorange C, Harbison CT, Graf Finckenstein F, Brahmer JR.

N Engl J Med · 2015

3.5/5

The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

Albert MS, DeKosky ST, Dickson D, Dubois B, Feldman HH, Fox NC, Gamst A, Holtzman DM, Jagust WJ, Petersen RC, Snyder PJ, Carrillo MC, Thies B, Phelps CH.

Alzheimers Dement · 2011

3.3/5

Integrated analysis of multimodal single-cell data

Hao Y, Hao S, Andersen-Nissen E, Mauck WM, Zheng S, Butler A, Lee MJ, Wilk AJ, Darby C, Zager M, Hoffman P, Stoeckius M, Papalexi E, Mimitou EP, Jain J, Srivastava A, Stuart T, Fleming LM, Yeung B, Rogers AJ, McElrath JM, Blish CA, Gottardo R, Smibert P, Satija R.

Cell · 2021

2.0/5

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Komor AC, Kim YB, Packer MS, Zuris JA, Liu DR.

Nature · 2016

3.0/5

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.

Mol Cell · 2017

2.8/5

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M.

Proc Natl Acad Sci U S A · 1998

2.3/5

Natural products in drug discovery: advances and opportunities

Atanasov AG, Zotchev SB, Dirsch VM, International Natural Product Sciences Taskforce, Supuran CT.

Nat Rev Drug Discov · 2021

4.0/5

Genetic screens in human cells using the CRISPR-Cas9 system

Wang T, Wei JJ, Sabatini DM, Lander ES.

Science · 2014

2.5/5

Ferroptosis: mechanisms, biology and role in disease

Jiang X, Jiang X, Stockwell BR, Conrad M.

Nat Rev Mol Cell Biol · 2021

3.5/5

Inflammation and Alzheimer's disease

Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, Cooper NR, Eikelenboom P, Emmerling M, Fiebich BL, Finch CE, Frautschy S, Griffin WS, Hampel H, Hull M, Landreth G, Lue L, Mrak R, Mackenzie IR, McGeer PL, O'Banion MK, Pachter J, Pasinetti G, Plata-Salaman C, Rogers J, Rydel R, Shen Y, Streit W, Strohmeyer R, Tooyoma I, Van Muiswinkel FL, Veerhuis R, Walker D, Webster S, Wegrzyniak B, Wenk G, Wyss-Coray T.

Neurobiol Aging · 2000

4.3/5

Determining cell type abundance and expression from bulk tissues with digital cytometry

Newman AM, Steen CB, Liu CL, Gentles AJ, Chaudhuri AA, Scherer F, Khodadoust MS, Esfahani MS, Luca BA, Steiner D, Diehn M, Alizadeh AA.

Nat Biotechnol · 2019

4.0/5

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, Skora AD, Luber BS, Azad NS, Laheru D, Biedrzycki B, Donehower RC, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Duffy SM, Goldberg RM, de la Chapelle A, Koshiji M, Bhaijee F, Huebner T, Hruban RH, Wood LD, Cuka N, Pardoll DM, Papadopoulos N, Kinzler KW, Zhou S, Cornish TC, Taube JM, Anders RA, Eshleman JR, Vogelstein B, Diaz LA.

N Engl J Med · 2015

2.8/5

Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease

Buckner RL, Sepulcre J, Talukdar T, Krienen FM, Liu H, Hedden T, Andrews-Hanna JR, Sperling RA, Johnson KA.

J Neurosci · 2009

3.0/5

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

Döhner H, Estey E, Grimwade D, Amadori S, Appelbaum FR, Büchner T, Dombret H, Ebert BL, Fenaux P, Larson RA, Levine RL, Lo-Coco F, Naoe T, Niederwieser D, Ossenkoppele GJ, Sanz M, Sierra J, Tallman MS, Tien HF, Wei AH, Löwenberg B, Bloomfield CD.

Blood · 2017

4.0/5

Biological Functions of Autophagy Genes: A Disease Perspective

Levine B, Kroemer G.

Cell · 2019

2.0/5

Neuropathological stageing of Alzheimer-related changes

Braak H, Braak E.

Acta Neuropathol · 1991

3.3/5

Pfam: The protein families database in 2021

Mistry J, Chuguransky S, Williams L, Qureshi M, Salazar GA, Sonnhammer ELL, Tosatto SCE, Paladin L, Raj S, Richardson LJ, Finn RD, Bateman A.

Nucleic Acids Res · 2021

2.8/5

Cholangiocarcinoma 2020: the next horizon in mechanisms and management

Banales JM, Marin JJG, Lamarca A, Rodrigues PM, Khan SA, Roberts LR, Cardinale V, Carpino G, Andersen JB, Braconi C, Calvisi DF, Perugorria MJ, Fabris L, Boulter L, Macias RIR, Gaudio E, Alvaro D, Gradilone SA, Strazzabosco M, Marzioni M, Coulouarn C, Fouassier L, Raggi C, Invernizzi P, Mertens JC, Moncsek A, Ilyas SI, Heimbach J, Koerkamp BG, Bruix J, Forner A, Bridgewater J, Valle JW, Gores GJ.

Nat Rev Gastroenterol Hepatol · 2020

2.8/5

The neuropathological diagnosis of Alzheimer's disease

DeTure MA, Dickson DW.

Mol Neurodegener · 2019

2.8/5

Blood-brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

Sweeney MD, Sagare AP, Zlokovic BV.

Nat Rev Neurol · 2018

3.3/5

The biology and management of non-small cell lung cancer

Herbst RS, Morgensztern D, Boshoff C.

Nature · 2018

3.5/5

A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles

Subramanian A, Narayan R, Corsello SM, Peck DD, Natoli TE, Lu X, Gould J, Davis JF, Tubelli AA, Asiedu JK, Lahr DL, Hirschman JE, Liu Z, Donahue M, Julian B, Khan M, Wadden D, Smith IC, Lam D, Liberzon A, Toder C, Bagul M, Orzechowski M, Enache OM, Piccioni F, Johnson SA, Lyons NJ, Berger AH, Shamji AF, Brooks AN, Vrcic A, Flynn C, Rosains J, Takeda DY, Hu R, Davison D, Lamb J, Ardlie K, Hogstrom L, Greenside P, Gray NS, Clemons PA, Silver S, Wu X, Zhao WN, Read-Button W, Wu X, Haggarty SJ, Ronco LV, Boehm JS, Schreiber SL, Doench JG, Bittker JA, Root DE, Wong B, Golub TR.

Cell · 2017

3.3/5

Alzheimer's disease

Scheltens P, Blennow K, Breteler MM, de Strooper B, Frisoni GB, Frisoni GB, Salloway S, Van der Flier WM.

Lancet · 2016

3.5/5

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

Trapnell C, Roberts A, Goff L, Pertea G, Kim D, Kelley DR, Pimentel H, Salzberg SL, Rinn JL, Pachter L.

Nat Protoc · 2012

2.5/5

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J.

Nature · 2000

2.3/5