Tom Garcia

Liked papers (23)

Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

Rizvi NA, Hellmann MD, Snyder A, Kvistborg P, Makarov V, Havel JJ, Lee W, Yuan J, Wong P, Ho TS, Miller ML, Rekhtman N, Moreira AL, Ibrahim F, Bruggeman C, Gasmi B, Zappasodi R, Maeda Y, Sander C, Garon EB, Merghoub T, Wolchok JD, Schumacher TN, Chan TA.

Science · 2015

The Immune Landscape of Cancer

Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS, Cancer Genome Atlas Research Network, Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich I.

Immunity · 2018

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

Pronk S, Páll S, Schulz R, Larsson P, Bjelkmar P, Apostolov R, Shirts MR, Smith JC, Kasson PM, van der Spoel D, Hess B, Lindahl E.

Bioinformatics · 2013

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Alvarez-Erviti L, Seow Y, Yin H, Betts C, Lakhal S, Wood MJ.

Nat Biotechnol · 2011

The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions

Oughtred R, Rust J, Chang C, Breitkreutz BJ, Stark C, Willems A, Boucher L, Leung G, Kolas N, Zhang F, Dolma S, Coulombe-Huntington J, Chatr-Aryamontri A, Dolinski K, Tyers M.

Protein Sci · 2021

TopHat: discovering splice junctions with RNA-Seq

Trapnell C, Pachter L, Salzberg SL.

Bioinformatics · 2009

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

Saunders AM, Strittmatter WJ, Schmechel D, George-Hyslop PH, Pericak-Vance MA, Joo SH, Rosi BL, Gusella JF, Crapper-MacLachlan DR, Alberts MJ.

Neurology · 1993

In vivo genome editing using Staphylococcus aureus Cas9

Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F.

Nature · 2015

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Komor AC, Kim YB, Packer MS, Zuris JA, Liu DR.

Nature · 2016

CRISPR-Cas systems for editing, regulating and targeting genomes

Sander JD, Joung JK.

Nat Biotechnol · 2014

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS.

Cell · 2013

SCENIC: single-cell regulatory network inference and clustering

Aibar S, González-Blas CB, Moerman T, Huynh-Thu VA, Imrichova H, Hulselmans G, Rambow F, Marine JC, Geurts P, Aerts J, van den Oord J, Atak ZK, Wouters J, Aerts S.

Nat Methods · 2017

Radiomics: Images Are More than Pictures, They Are Data

Gillies RJ, Kinahan PE, Hricak H.

Radiology · 2016

Robust enumeration of cell subsets from tissue expression profiles

Newman AM, Liu CL, Green MR, Gentles AJ, Feng W, Xu Y, Hoang CD, Diehn M, Alizadeh AA.

Nat Methods · 2015

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

Fu Y, Foden JA, Khayter C, Maeder ML, Reyon D, Joung JK, Sander JD.

Nat Biotechnol · 2013

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA.

Science · 1993

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

Kim D, Paggi JM, Park C, Bennett C, Salzberg SL.

Nat Biotechnol · 2019

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M.

Proc Natl Acad Sci U S A · 1998

Next-generation characterization of the Cancer Cell Line Encyclopedia

Ghandi M, Huang FW, Jané-Valbuena J, Kryukov GV, Lo CC, McDonald ER, Barretina J, Gelfand ET, Bielski CM, Li H, Hu K, Andreev-Drakhlin AY, Kim J, Hess JM, Haas BJ, Aguet F, Weir BA, Rothberg MV, Paolella BR, Lawrence MS, Akbani R, Lu Y, Tiv HL, Gokhale PC, de Weck A, Mansour AA, Oh C, Shih J, Hadi K, Rosen Y, Bistline J, Venkatesan K, Reddy A, Sonkin D, Liu M, Lehar J, Korn JM, Porter DA, Jones MD, Golji J, Caponigro G, Taylor JE, Dunning CM, Creech AL, Warren AC, McFarland JM, Zamanighomi M, Kauffmann A, Stransky N, Imielinski M, Maruvka YE, Cherniack AD, Tsherniak A, Vazquez F, Jaffe JD, Lane AA, Weinstock DM, Johannessen CM, Morrissey MP, Stegmeier F, Schlegel R, Hahn WC, Getz G, Mills GB, Boehm JS, Golub TR, Garraway LA, Sellers WR.

Nature · 2019

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Cancer Genome Atlas Research Network.

Nature · 2008

A new coronavirus associated with human respiratory disease in China

Wu F, Zhao S, Yu B, Chen YM, Wang W, Song ZG, Hu Y, Tao ZW, Tian JH, Pei YY, Yuan ML, Zhang YL, Dai FH, Liu Y, Wang QM, Zheng JJ, Xu L, Holmes EC, Zhang YZ.

Nature · 2020

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system

Zetsche B, Gootenberg JS, Abudayyeh OO, Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der Oost J, Regev A, Koonin EV, Zhang F.

Cell · 2015

A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles

Subramanian A, Narayan R, Corsello SM, Peck DD, Natoli TE, Lu X, Gould J, Davis JF, Tubelli AA, Asiedu JK, Lahr DL, Hirschman JE, Liu Z, Donahue M, Julian B, Khan M, Wadden D, Smith IC, Lam D, Liberzon A, Toder C, Bagul M, Orzechowski M, Enache OM, Piccioni F, Johnson SA, Lyons NJ, Berger AH, Shamji AF, Brooks AN, Vrcic A, Flynn C, Rosains J, Takeda DY, Hu R, Davison D, Lamb J, Ardlie K, Hogstrom L, Greenside P, Gray NS, Clemons PA, Silver S, Wu X, Zhao WN, Read-Button W, Wu X, Haggarty SJ, Ronco LV, Boehm JS, Schreiber SL, Doench JG, Bittker JA, Root DE, Wong B, Golub TR.

Cell · 2017