Liked papers (28)
Velvet: algorithms for de novo short read assembly using de Bruijn graphs
Zerbino DR, Birney E.
Genome Res · 2008
Lipid nanoparticles for mRNA delivery
Hou X, Zaks T, Langer R, Dong Y.
Nat Rev Mater · 2021
The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences
Perez-Riverol Y, Bai J, Bandla C, García-Seisdedos D, Hewapathirana S, Kamatchinathan S, Kundu DJ, Prakash A, Frericks-Zipper A, Eisenacher M, Walzer M, Wang S, Brazma A, Vizcaíno JA.
Nucleic Acids Res · 2022
Super-enhancers in the control of cell identity and disease
Hnisz D, Abraham BJ, Lee TI, Lau A, Saint-André V, Sigova AA, Hoke HA, Young RA.
Cell · 2013
The mutational constraint spectrum quantified from variation in 141,456 humans
Karczewski KJ, Francioli LC, Tiao G, Cummings BB, Alföldi J, Wang Q, Collins RL, Laricchia KM, Ganna A, Birnbaum DP, Gauthier LD, Brand H, Solomonson M, Watts NA, Rhodes D, Singer-Berk M, England EM, Seaby EG, Kosmicki JA, Walters RK, Tashman K, Farjoun Y, Banks E, Poterba T, Wang A, Seed C, Whiffin N, Chong JX, Samocha KE, Pierce-Hoffman E, Zappala Z, O'Donnell-Luria AH, Minikel EV, Weisburd B, Lek M, Ware JS, Vittal C, Armean IM, Bergelson L, Cibulskis K, Connolly KM, Covarrubias M, Donnelly S, Ferriera S, Gabriel S, Gentry J, Gupta N, Jeandet T, Kaplan D, Llanwarne C, Munshi R, Novod S, Petrillo N, Roazen D, Ruano-Rubio V, Saltzman A, Schleicher M, Soto J, Tibbetts K, Tolonen C, Wade G, Talkowski ME, Genome Aggregation Database Consortium, Neale BM, Daly MJ, MacArthur DG.
Nature · 2020
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
Alvarez-Erviti L, Seow Y, Yin H, Betts C, Lakhal S, Wood MJ.
Nat Biotechnol · 2011
Oncology meets immunology: the cancer-immunity cycle
Chen DS, Mellman I.
Immunity · 2013
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR.
Nature · 2017
Integrated analysis of multimodal single-cell data
Hao Y, Hao S, Andersen-Nissen E, Mauck WM, Zheng S, Butler A, Lee MJ, Wilk AJ, Darby C, Zager M, Hoffman P, Stoeckius M, Papalexi E, Mimitou EP, Jain J, Srivastava A, Stuart T, Fleming LM, Yeung B, Rogers AJ, McElrath JM, Blish CA, Gottardo R, Smibert P, Satija R.
Cell · 2021
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
Leng F, Edison P.
Nat Rev Neurol · 2021
Immune checkpoint blockade: a common denominator approach to cancer therapy
Topalian SL, Drake CG, Pardoll DM.
Cancer Cell · 2015
Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial
El-Khoueiry AB, Sangro B, Yau T, Crocenzi TS, Kudo M, Hsu C, Kim TY, Choo SP, Trojan J, Welling TH, Meyer T, Kang YK, Yeo W, Chopra A, Anderson J, Dela Cruz C, Lang L, Neely J, Tang H, Dastani HB, Melero I.
Lancet · 2017
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
Eyquem J, Mansilla-Soto J, Giavridis T, van der Stegen SJ, Hamieh M, Cunanan KM, Odak A, Gönen M, Sadelain M.
Nature · 2017
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
Doench JG, Fusi N, Sullender M, Hegde M, Vaimberg EW, Donovan KF, Smith I, Tothova Z, Wilen C, Orchard R, Virgin HW, Listgarten J, Root DE.
Nat Biotechnol · 2016
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide
Haass C, Selkoe DJ.
Nat Rev Mol Cell Biol · 2007
Inference and analysis of cell-cell communication using CellChat
Jin S, Guerrero-Juarez CF, Zhang L, Chang I, Ramos R, Kuan CH, Myung P, Plikus MV, Nie Q.
Nat Commun · 2021
A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β
Iliff JJ, Wang M, Liao Y, Plogg BA, Peng W, Gundersen GA, Benveniste H, Vates GE, Deane R, Goldman SA, Nagelhus EA, Nedergaard M.
Sci Transl Med · 2012
The Genotype-Tissue Expression (GTEx) project
GTEx Consortium.
Nat Genet · 2013
Single-cell transcriptomic analysis of Alzheimer's disease
Mathys H, Davila-Velderrain J, Peng Z, Gao F, Mohammadi S, Young JZ, Menon M, He L, Abdurrob F, Jiang X, Martorell AJ, Ransohoff RM, Hafler BP, Bennett DA, Kellis M, Tsai LH.
Nature · 2019
The blockade of immune checkpoints in cancer immunotherapy
Pardoll DM.
Nat Rev Cancer · 2012
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, Heun R, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Holmans PA, O'Donovan M, Owen MJ, Williams J.
Nat Genet · 2009
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J.
Nature · 2000
Most mammalian mRNAs are conserved targets of microRNAs
Friedman RC, Farh KK, Burge CB, Bartel DP.
Genome Res · 2009
Long COVID: major findings, mechanisms and recommendations
Davis HE, McCorkell L, Vogel JM, Topol EJ.
Nat Rev Microbiol · 2023
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
Gaj T, Gersbach CA, Barbas CF.
Trends Biotechnol · 2013
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, Zhang F, Jaenisch R.
Cell · 2013
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
Ran FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y, Zhang F.
Cell · 2013
CRISPResso2 provides accurate and rapid genome editing sequence analysis
Clement K, Rees H, Canver MC, Gehrke JM, Farouni R, Hsu JY, Cole MA, Liu DR, Joung JK, Bauer DE, Pinello L.
Nat Biotechnol · 2019