Jonas Brown

All read papers (42)

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary

Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D, Hawkins C, Ng HK, Pfister SM, Reifenberger G, Soffietti R, von Deimling A, Ellison DW.

Neuro Oncol · 2021

2.0/5

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

Pronk S, Páll S, Schulz R, Larsson P, Bjelkmar P, Apostolov R, Shirts MR, Smith JC, Kasson PM, van der Spoel D, Hess B, Lindahl E.

Bioinformatics · 2013

4.0/5

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

Richards S, Aziz N, Bale S, Bick D, Das S, Gastier-Foster J, Grody WW, Hegde M, Lyon E, Spector E, Voelkerding K, Rehm HL, ACMG Laboratory Quality Assurance Committee.

Genet Med · 2015

3.8/5

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Grzeschik KH, Multhaup G, Beyreuther K, Müller-Hill B.

Nature · 1987

3.0/5

NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control

Böttcher JP, Bonavita E, Chakravarty P, Blees H, Cabeza-Cabrerizo M, Sammicheli S, Rogers NC, Sahai E, Zelenay S, Reis e Sousa C

Cell · 2018

4.5/5

Comprehensive molecular characterization of human colon and rectal cancer

Cancer Genome Atlas Network.

Nature · 2012

1.0/5

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ, MISEV Consortium, Théry C, Witwer KW.

J Extracell Vesicles · 2024

2.8/5

An integrated map of genetic variation from 1,092 human genomes

1000 Genomes Project Consortium, Abecasis GR, Auton A, Brooks LD, DePristo MA, Durbin RM, Handsaker RE, Kang HM, Marth GT, McVean GA.

Nature · 2012

3.3/5

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

Klunk WE, Engler H, Nordberg A, Wang Y, Blomqvist G, Holt DP, Bergström M, Savitcheva I, Huang GF, Estrada S, Ausén B, Debnath ML, Barletta J, Price JC, Sandell J, Lopresti BJ, Wall A, Koivisto P, Antoni G, Mathis CA, Långström B.

Ann Neurol · 2004

3.8/5

A Robust CRISPR/Cas9 System for Convenient, High-Efficiency Multiplex Genome Editing in Monocot and Dicot Plants

Ma X, Zhang Q, Zhu Q, Liu W, Chen Y, Qiu R, Wang B, Yang Z, Li H, Lin Y, Xie Y, Shen R, Chen S, Wang Z, Chen Y, Guo J, Chen L, Zhao X, Dong Z, Liu YG.

Mol Plant · 2015

2.3/5

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

Coronaviridae Study Group of the International Committee on Taxonomy of Viruses.

Nat Microbiol · 2020

2.3/5

Coactivator condensation at super-enhancers links phase separation and gene control

Sabari BR, Dall'Agnese A, Boija A, Klein IA, Coffey EL, Shrinivas K, Abraham BJ, Hannett NM, Zamudio AV, Manteiga JC, Li CH, Guo YE, Day DS, Schuijers J, Vasile E, Malik S, Hnisz D, Lee TI, Cisse II, Roeder RG, Sharp PA, Chakraborty AK, Young RA.

Science · 2018

3.5/5

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Alvarez-Erviti L, Seow Y, Yin H, Betts C, Lakhal S, Wood MJ.

Nat Biotechnol · 2011

4.0/5

The human genome browser at UCSC

Kent WJ, Sugnet CW, Furey TS, Roskin KM, Pringle TH, Zahler AM, Haussler D.

Genome Res · 2002

4.3/5

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

Larkin J, Chiarion-Sileni V, Gonzalez R, Grob JJ, Cowey CL, Lao CD, Schadendorf D, Dummer R, Smylie M, Rutkowski P, Ferrucci PF, Hill A, Wagstaff J, Carlino MS, Haanen JB, Maio M, Marquez-Rodas I, McArthur GA, Ascierto PA, Long GV, Callahan MK, Postow MA, Grossmann K, Sznol M, Dreno B, Bastholt L, Yang A, Rollin LM, Horak C, Hodi FS, Wolchok JD.

N Engl J Med · 2015

2.3/5

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

Döhner H, Estey E, Grimwade D, Amadori S, Appelbaum FR, Büchner T, Dombret H, Ebert BL, Fenaux P, Larson RA, Levine RL, Lo-Coco F, Naoe T, Niederwieser D, Ossenkoppele GJ, Sanz M, Sierra J, Tallman MS, Tien HF, Wei AH, Löwenberg B, Bloomfield CD.

Blood · 2017

2.3/5

Structure, function and diversity of the healthy human microbiome

Human Microbiome Project Consortium.

Nature · 2012

3.5/5

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA.

Science · 1993

3.8/5

Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells

Meyers RM, Bryan JG, McFarland JM, Weir BA, Sizemore AE, Xu H, Dharia NV, Montgomery PG, Cowley GS, Pantel S, Goodale A, Lee Y, Ali LD, Jiang G, Lubonja R, Harrington WF, Strickland M, Wu T, Hawes DC, Zhivich VA, Wyatt MR, Kalani Z, Chang JJ, Okamoto M, Stegmaier K, Golub TR, Boehm JS, Vazquez F, Root DE, Hahn WC, Tsherniak A.

Nat Genet · 2017

3.0/5

Wnt signaling in cancer

Zhan T, Rindtorff N, Boutros M.

Oncogene · 2017

2.0/5

The future of immune checkpoint therapy

Sharma P, Allison JP.

Science · 2015

2.8/5

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ.

Nat Med · 2008

4.3/5

Genetic screens in human cells using the CRISPR-Cas9 system

Wang T, Wei JJ, Sabatini DM, Lander ES.

Science · 2014

2.5/5

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

Kim D, Paggi JM, Park C, Bennett C, Salzberg SL.

Nat Biotechnol · 2019

2.8/5

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China

Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, Zhao Y, Li Y, Wang X, Peng Z.

JAMA · 2020

1.8/5

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE.

Science · 2014

2.3/5

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

Grundke-Iqbal I, Iqbal K, Tung YC, Quinlan M, Wisniewski HM, Binder LI.

Proc Natl Acad Sci U S A · 1986

3.3/5

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

Livingston G, Huntley J, Sommerlad A, Ames D, Ballard C, Banerjee S, Brayne C, Burns A, Cohen-Mansfield J, Cooper C, Costafreda SG, Dias A, Fox N, Gitlin LN, Howard R, Kales HC, Kivimäki M, Larson EB, Ogunniyi A, Orgeta V, Ritchie K, Rockwood K, Sampson EL, Samus Q, Schneider LS, Selbæk G, Teri L, Mukadam N.

Lancet · 2020

3.3/5

Cancer immunotherapy using checkpoint blockade

Ribas A, Wolchok JD.

Science · 2018

2.3/5

A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β

Iliff JJ, Wang M, Liao Y, Plogg BA, Peng W, Gundersen GA, Benveniste H, Vates GE, Deane R, Goldman SA, Nagelhus EA, Nedergaard M.

Sci Transl Med · 2012

3.5/5

A framework for advancing our understanding of cancer-associated fibroblasts

Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, Kolonin MG, Maki RG, Powers RS, Puré E, Ramirez DC, Scherz-Shouval R, Sherman MH, Stewart S, Tlsty TD, Tuveson DA, Watt FM, Weaver V, Weeraratna AT, Werb Z.

Nat Rev Cancer · 2020

2.8/5

A comprehensive set of sequence analysis programs for the VAX

Devereux J, Haeberli P, Smithies O.

Nucleic Acids Res · 1984

3.5/5

Metagenomic biomarker discovery and explanation

Segata N, Izard J, Waldron L, Gevers D, Miropolsky L, Garrett WS, Huttenhower C.

Genome Biol · 2011

2.5/5

Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection

Eyquem J, Mansilla-Soto J, Giavridis T, van der Stegen SJ, Hamieh M, Cunanan KM, Odak A, Gönen M, Sadelain M.

Nature · 2017

2.0/5

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

Pertea M, Pertea GM, Antonescu CM, Chang TC, Mendell JT, Salzberg SL.

Nat Biotechnol · 2015

2.3/5

Predicting effective microRNA target sites in mammalian mRNAs

Agarwal V, Bell GW, Nam JW, Bartel DP.

Elife · 2015

3.0/5

Alzheimer's disease

Scheltens P, De Strooper B, Kivipelto M, Holstege H, Chételat G, Teunissen CE, Cummings J, van der Flier WM.

Lancet · 2021

1.8/5

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

Zlokovic BV.

Nat Rev Neurosci · 2011

4.5/5

Chimeric antigen receptor T cells for sustained remissions in leukemia

Maude SL, Frey N, Shaw PA, Aplenc R, Barrett DM, Bunin NJ, Chew A, Gonzalez VE, Zheng Z, Lacey SF, Mahnke YD, Melenhorst JJ, Rheingold SR, Shen A, Teachey DT, Levine BL, June CH, Porter DL, Grupp SA.

N Engl J Med · 2014

2.5/5

Designing hydrogels for controlled drug delivery

Li J, Mooney DJ.

Nat Rev Mater · 2016

2.8/5

Microglia Function in the Central Nervous System During Health and Neurodegeneration

Colonna M, Butovsky O.

Annu Rev Immunol · 2017

2.3/5

DNA targeting specificity of RNA-guided Cas9 nucleases

Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F.

Nat Biotechnol · 2013

2.5/5