All read papers (29)
Cluster analysis and display of genome-wide expression patterns
Eisen MB, Spellman PT, Brown PO, Botstein D.
Proc Natl Acad Sci U S A · 1998
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E.
Science · 2012
Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
Chen EY, Tan CM, Kou Y, Duan Q, Wang Z, Meirelles GV, Clark NR, Ma'ayan A.
BMC Bioinformatics · 2013
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
Grundke-Iqbal I, Iqbal K, Tung YC, Quinlan M, Wisniewski HM, Binder LI.
Proc Natl Acad Sci U S A · 1986
DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants
Piñero J, Bravo À, Queralt-Rosinach N, Gutiérrez-Sacristán A, Deu-Pons J, Centeno E, García-García J, Sanz F, Furlong LI.
Nucleic Acids Res · 2017
Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria
Dubois B, Feldman HH, Jacova C, Dekosky ST, Barberger-Gateau P, Cummings J, Delacourte A, Galasko D, Gauthier S, Jicha G, Meguro K, O'brien J, Pasquier F, Robert P, Rossor M, Salloway S, Stern Y, Visser PJ, Scheltens P.
Lancet Neurol · 2007
Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial
Rittmeyer A, Barlesi F, Waterkamp D, Park K, Ciardiello F, von Pawel J, Gadgeel SM, Hida T, Kowalski DM, Dols MC, Cortinovis DL, Leach J, Polikoff J, Barrios C, Kabbinavar F, Frontera OA, De Marinis F, Turna H, Lee JS, Ballinger M, Kowanetz M, He P, Chen DS, Sandler A, Gandara DR, OAK Study Group.
Lancet · 2017
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G.
Science · 1996
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
Tsai SQ, Zheng Z, Nguyen NT, Liebers M, Topkar VV, Thapar V, Wyvekens N, Khayter C, Iafrate AJ, Le LP, Aryee MJ, Joung JK.
Nat Biotechnol · 2015
Complement and microglia mediate early synapse loss in Alzheimer mouse models
Hong S, Beja-Glasser VF, Nfonoyim BM, Frouin A, Li S, Ramakrishnan S, Merry KM, Shi Q, Rosenthal A, Barres BA, Lemere CA, Selkoe DJ, Stevens B.
Science · 2016
A framework for advancing our understanding of cancer-associated fibroblasts
Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, Kolonin MG, Maki RG, Powers RS, Puré E, Ramirez DC, Scherz-Shouval R, Sherman MH, Stewart S, Tlsty TD, Tuveson DA, Watt FM, Weaver V, Weeraratna AT, Werb Z.
Nat Rev Cancer · 2020
DNA targeting specificity of RNA-guided Cas9 nucleases
Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F.
Nat Biotechnol · 2013
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
Hilton IB, D'Ippolito AM, Vockley CM, Thakore PI, Crawford GE, Reddy TE, Gersbach CA.
Nat Biotechnol · 2015
Ferroptosis: mechanisms, biology and role in disease
Jiang X, Jiang X, Stockwell BR, Conrad M.
Nat Rev Mol Cell Biol · 2021
Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads
Wick RR, Judd LM, Gorrie CL, Holt KE.
PLoS Comput Biol · 2017
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
Gootenberg JS, Abudayyeh OO, Kellner MJ, Joung J, Collins JJ, Zhang F.
Science · 2018
Natural products in drug discovery: advances and opportunities
Atanasov AG, Zotchev SB, Dirsch VM, International Natural Product Sciences Taskforce, Supuran CT.
Nat Rev Drug Discov · 2021
Understanding the tumor immune microenvironment (TIME) for effective therapy
Binnewies M, Roberts EW, Kersten K, Chan V, Fearon DF, Merad M, Coussens LM, Gabrilovich DI, Ostrand-Rosenberg S, Hedrick CC, Vonderheide RH, Pittet MJ, Jain RK, Zou W, Howcroft TK, Woodhouse EC, Weinberg RA, Krummel MF.
Nat Med · 2018
A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease
Jessen F, Amariglio RE, van Boxtel M, Breteler M, Ceccaldi M, Chételat G, Dubois B, Dufouil C, Ellis KA, van der Flier WM, Glodzik L, van Harten AC, de Leon MJ, McHugh P, Mielke MM, Molinuevo JL, Mosconi L, Osorio RS, Perrotin A, Petersen RC, Rabin LA, Rami L, Reisberg B, Rentz DM, Sachdev PS, de la Sayette V, Saykin AJ, Scheltens P, Shulman MB, Slavin MJ, Sperling RA, Stewart R, Uspenskaya O, Vellas B, Visser PJ, Wagner M, Subjective Cognitive Decline Initiative (SCD-I) Working Group.
Alzheimers Dement · 2014
RNA-programmed genome editing in human cells
Jinek M, East A, Cheng A, Lin S, Ma E, Doudna J.
Elife · 2013
Genetic screens in human cells using the CRISPR-Cas9 system
Wang T, Wei JJ, Sabatini DM, Lander ES.
Science · 2014
Loop-mediated isothermal amplification of DNA
Notomi T, Okayama H, Masubuchi H, Yonekawa T, Watanabe K, Amino N, Hase T.
Nucleic Acids Res · 2000
Immune checkpoint blockade: a common denominator approach to cancer therapy
Topalian SL, Drake CG, Pardoll DM.
Cancer Cell · 2015
Long COVID: major findings, mechanisms and recommendations
Davis HE, McCorkell L, Vogel JM, Topol EJ.
Nat Rev Microbiol · 2023
The biology and management of non-small cell lung cancer
Herbst RS, Morgensztern D, Boshoff C.
Nature · 2018
The 2021 WHO Classification of Tumors of the Central Nervous System: a summary
Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D, Hawkins C, Ng HK, Pfister SM, Reifenberger G, Soffietti R, von Deimling A, Ellison DW.
Neuro Oncol · 2021
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
Öhlund D, Handly-Santana A, Biffi G, Elyada E, Almeida AS, Ponz-Sarvise M, Corbo V, Oni TE, Hearn SA, Lee EJ, Chio II, Hwang CI, Tiriac H, Baker LA, Engle DD, Feig C, Kultti A, Egeblad M, Fearon DT, Crawford JM, Clevers H, Park Y, Tuveson DA.
J Exp Med · 2017
Pathways towards and away from Alzheimer's disease
Mattson MP.
Nature · 2004
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Komor AC, Kim YB, Packer MS, Zuris JA, Liu DR.
Nature · 2016